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2,3,4-三氟苯胺

2,3,4-三氟苯胺用途

用于合成抗菌药氟嗪酸和美沙星药物等。还用来生产喹诺酮类抗菌药。

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2,3,4-三氟苯胺名称

[ CAS 号 ]:
3862-73-5

[ 中文名 ]:
2,3,4-三氟苯胺

[ 英文名 ]:
2,3,4-Trifluoroaniline

[英文别名 ]:

Benzenamine, 2,3,4-trifluoro-
ZR BF CF DF
2,3,4-Trifluoroaniline
EINECS 253-703-1
MFCD00011737
2,3,4-Trifluorobenzenamine

2,3,4-三氟苯胺物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
173.8±0.0 °C at 760 mmHg

[ 熔点 ]:
14-15°C

[ 分子式 ]:
C₆H₄F₃N

[ 分子量 ]:
147.098

[ 闪点 ]:
68.3±0.0 °C

[ 精确质量 ]:
147.029587

[ PSA ]:
26.02000

[ LogP ]:
1.79

[ 外观性状 ]:
无色至淡黄色液体

[ 蒸汽压 ]:
1.2±0.3 mmHg at 25°C

[ 折射率 ]:
1.496

[ 储存条件 ]:
室温

2,3,4-三氟苯胺MSDS

详细MSDS(安全技术说明书)

2,3,4-三氟苯胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CY1211500

CHEMICAL NAME :: Benzenamine, 2,3,4-trifluoro-

CAS REGISTRY NUMBER :: 3862-73-5

BEILSTEIN REFERENCE NO. :: 3245609

LAST UPDATED :: 199712

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C6-H4-F3-N

MOLECULAR WEIGHT :: 147.11

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,61,1990

TYPE OF TEST :: Rinsed with water

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,61,1990 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 699 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - cyanosis Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,61,1990

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2,3,4-三氟苯胺安全信息

[ 符号 ]:

GHS05, GHS07, GHS08, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302 + H312-H315-H318-H373-H411

[ 警示性声明 ]:
P273-P280-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R21/22;R38;R41;R48/22;R51/53

[ 安全声明 (欧洲) ]:
S23-S26-S36/37/39-S61

[ 危险品运输编码 ]:
UN 3082 9/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
CY1211500

[ 包装等级 ]:
III

[ 危险类别 ]:
9.0

[ 海关编码 ]:
29214210

2,3,4-三氟苯胺合成路线

详细合成路线

2,3,4-三氟苯胺上下游产品

2,3,4-三氟苯胺上游产品

2,3,4-三氟苯胺下游产品

2,3,4-三氟苯胺制备

用1,2,3-三氟-4-硝基苯经还原制得。

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2,3,4-三氟苯胺海关

[ 海关编码 ]: 29214210

2,3,4-三氟苯胺文献

Study on Synthesis of 2, 3, 4-Trifluoroaniline. Tai-biaoZ, et al.

Fine Chemicals , Z1, (2007)

Thermochemical reaction of 7-azido-1-ethyl-6, 8-difluoroquinolone-3-carboxylate with heterocyclic amines. An expeditious synthesis of novel fluoroquinolone derivatives. Leyva S and Leyva E.

Tetrahedron 63(9) , 2093-97, (2007)

更多文献

2,3,4-三氟苯胺

2,3,4-三氟苯胺用途

2,3,4-三氟苯胺名称

2,3,4-三氟苯胺物理化学性质

2,3,4-三氟苯胺MSDS

详细MSDS(安全技术说明书)

2,3,4-三氟苯胺毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

2,3,4-三氟苯胺安全信息

2,3,4-三氟苯胺合成路线

详细合成路线

2,3,4-三氟苯胺上下游产品

2,3,4-三氟苯胺上游产品

2,3,4-三氟苯胺下游产品

2,3,4-三氟苯胺制备

2,3,4-三氟苯胺海关

2,3,4-三氟苯胺文献

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