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圣草酚-7-O-葡萄糖苷

圣草酚-7-O-葡萄糖苷用途

枇杷黄-7-O-葡萄糖苷(枇杷黄-7-O-β-D-葡萄糖苷)是一种黄酮类化合物,是一种有效的自由基清除剂。Eriodictyl-7-O-葡萄糖苷也是一种Nrf2激活剂,对顺铂诱导的毒性具有保护作用[1]。

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圣草酚-7-O-葡萄糖苷名称

[ CAS 号 ]:
38965-51-4

[ 中文名 ]:
圣草酚-7-O-葡糖苷

[ 英文名 ]:
Eriodictyol-7-O-glucoside

[英文别名 ]:

3',4',5,7-Tetrahydroxyflavanone-7-glucoside
ERIODICTYOL-7-GLUCOSIDE
pyracanthoside
eriodictyol-7-O-glucoside

圣草酚-7-O-葡萄糖苷生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> NF-κB信号通路 >> KEAP1-Nrf2

研究领域 >> 代谢疾病

[ 靶点 ]

Nrf2[1]

[参考文献]

[1]. Hu Q, et, al. Eriodictyol-7-O-glucoside, a novel Nrf2 activator, confers protection against cisplatin-induced toxicity. Food Chem Toxicol. 2012 Jun;50(6):1927-32.

圣草酚-7-O-葡萄糖苷物理化学性质

[ 密度 ]:
1.7±0.1 g/cm3

[ 沸点 ]:
841.0±65.0 °C at 760 mmHg

[ 熔点 ]:
171-176ºC

[ 分子式 ]:
C₂₁H₂₂O₁₁

[ 分子量 ]:
450.393

[ 闪点 ]:
296.9±27.8 °C

[ 精确质量 ]:
450.116211

[ PSA ]:
186.37000

[ LogP ]:
0.22

[ 蒸汽压 ]:
0.0±3.3 mmHg at 25°C

[ 折射率 ]:
1.713

[ 储存条件 ]:
2-8°C

圣草酚-7-O-葡萄糖苷MSDS

详细MSDS(安全技术说明书)

圣草酚-7-O-葡萄糖苷安全信息

[ 安全声明 (欧洲) ]:
22-24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

圣草酚-7-O-葡萄糖苷文献

Two new hepatoprotective stilbene glycosides from Acer mono leaves.

J. Nat. Prod. 68 , 101-3, (2005)

Two new stilbene glycosides, 5-O-methyl-(E)-resveratrol 3-O-beta-d-glucopyranoside (1) and 5-O-methyl-(E)-resveratrol 3-O-beta-D-apiofuranosyl-(1-->6)-beta-d-glucopyranoside (2), were isolated from th...

Eriodictyol-7-O-glucoside, a novel Nrf2 activator, confers protection against cisplatin-induced toxicity

Food Chem. Toxicol. 50 , 1927-1932, (2012)

Graphical abstract Eriodictyol-7-O-glucoside was identified as a novel Nrf2 activator and the present study demonstrated the efficacy of the compound in battling cisplatin-induced toxicity. [Display o...

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