4-过氧化氢异环磷酰胺
4-过氧化氢异环磷酰胺用途
4-过氧化氢异环磷酰胺名称
[ CAS 号 ]:
39800-28-7
[ 中文名 ]:
4-过氧化氢异环磷酰胺
[ 英文名 ]:
2H-1,3,2-Oxazaphosphorin-2-amine,N,3-bis(2-chloroethyl)tetrahydro-4-hydroperoxy-, 2-oxide
[英文别名 ]:
- Hydroperoxyisophosphamide
- 4-Hydroperoxyisophosphamid
- 4-Hydroperoxyifosfamid
- asta6760
- 4-hydroperoxyisophosphamide
4-过氧化氢异环磷酰胺生物活性
[ 描述 ]:
[ 相关类别 ]:
[参考文献]
4-过氧化氢异环磷酰胺物理化学性质
[ 密度 ]:
1.46g/cm3
[ 沸点 ]:
419.9ºC at 760mmHg
[ 分子式 ]:
C7H15Cl2N2O4P
[ 分子量 ]:
293.08
[ 闪点 ]:
207.8ºC
[ 精确质量 ]:
292.01500
[ PSA ]:
80.84000
[ LogP ]:
2.02850
[ 折射率 ]:
1.525
4-过氧化氢异环磷酰胺毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MX2435000
- CHEMICAL NAME :
- Hydroperoxide, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro- 2H-1,3,2-oxazaphospho rin- 4-yl-, P-oxide
- CAS REGISTRY NUMBER :
- 39800-28-7
- LAST UPDATED :
- 199310
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C7-H15-Cl2-N2-O4-P
- MOLECULAR WEIGHT :
- 293.11
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CTRRDO Cancer Treatment Reports. (Washington, DC) V.60-71, 1976-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 60,361,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 220 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CTRRDO Cancer Treatment Reports. (Washington, DC) V.60-71, 1976-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 60,361,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 230 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CTRRDO Cancer Treatment Reports. (Washington, DC) V.60-71, 1976-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 60,361,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 230 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CTRRDO Cancer Treatment Reports. (Washington, DC) V.60-71, 1976-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 60,361,1976
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