比立哌隆
比立哌隆名称
比立哌隆物理化学性质
[ 密度 ]:
1.29g/cm3
[ 沸点 ]:
594.2ºC at 760 mmHg
[ 分子式 ]:
C24H26FN3O
[ 分子量 ]:
391.48100
[ 闪点 ]:
313.2ºC
[ 精确质量 ]:
391.20600
[ PSA ]:
39.34000
[ LogP ]:
3.88820
[ 折射率 ]:
1.668
[ 储存条件 ]:
库房低温通风干燥
比立哌隆毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EU4167000
- CAS REGISTRY NUMBER :
- 41510-23-0
- LAST UPDATED :
- 199107
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C24-H26-F-N3-O
- MOLECULAR WEIGHT :
- 391.53
- WISWESSER LINE NOTATION :
- T D6 B656 FN IN LMTT&&J F3VR DF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 3,803,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay) Behavioral - ataxia
- REFERENCE :
- EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 17,312,1982
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