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4-苯基-1,2,3,6-四氢吡啶盐酸盐

4-苯基-1,2,3,6-四氢吡啶盐酸盐名称

[ CAS 号 ]:
43064-12-6

[ 中文名 ]:
1,2,3,6-四氢-4-苯基吡啶盐酸盐

[ 英文名 ]:
4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride

[中文别名 ]:

4-苯基-1,2,3,6-四氢吡啶盐酸盐

[英文别名 ]:

4-Phenyl-1,2,3,6-tetrahydropyridinehydrochloride
4-phenyl-1,2,3,6-tetrahydropyridine,hydrochloride
4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride
1,2,3,6-Tetrahydro-4-phenylpyridine Hydrochloride
EINECS 256-071-5
MFCD00012752

4-苯基-1,2,3,6-四氢吡啶盐酸盐物理化学性质

[ 沸点 ]:
267.9ºC at 760 mmHg

[ 熔点 ]:
200-204ºC

[ 分子式 ]:
C₁₁H₁₄ClN

[ 分子量 ]:
195.689

[ 闪点 ]:
119.9ºC

[ 精确质量 ]:
195.081482

[ PSA ]:
12.03000

[ LogP ]:
3.19410

[ 外观性状 ]:
淡棕色粉末

[ 储存条件 ]:
室温

[ 水溶解性 ]:
Soluble

4-苯基-1,2,3,6-四氢吡啶盐酸盐MSDS

4-苯基-1,2,3,6-四氢吡啶盐酸盐安全信息

[ 符号 ]:

GHS06, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301-H311-H331-H351

[ 警示性声明 ]:
P261-P280-P301 + P310-P311

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T: Toxic;

[ 风险声明 (欧洲) ]:
R23/24/25;R40

[ 安全声明 (欧洲) ]:
S28-S36/37/39-S38-S45

[ 危险品运输编码 ]:
UN 2811

[ WGK德国 ]:
3

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

4-苯基-1,2,3,6-四氢吡啶盐酸盐合成路线

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4-苯基-1,2,3,6-四氢吡啶盐酸盐文献

4-Phenyl-1,2,3,6-tetrahydropyridine, an excellent fragment to improve the potency of PARP-1 inhibitors.

Bioorg. Med. Chem. Lett. 15(19) , 4221-5, (2005)

We have shown that a 4-phenyl-1,2,3,6-tetrahydropyridine fragment plays an important role in improving inhibitory potency against poly(ADP-ribose) polymerase-1 (PARP-1). Various benzamide analogues li...

Polygalae radix inhibits toxin-induced neuronal death in the Parkinson's disease models.

J. Ethnopharmacol. 134(2) , 414-21, (2011)

Polygalae radix, the root of Polygala tenuifolia Willd, has commonly been used for the treatment of amnesia and anxiety in traditional Korean medicine. The aim of this study was to investigate its neu...

Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.

PLoS ONE 4(9) , e7247, (2009)

It has been shown that molecular hydrogen (H(2)) acts as a therapeutic antioxidant and suppresses brain injury by buffering the effects of oxidative stress. Chronic oxidative stress causes neurodegene...

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