2,5-Cyclohexadiene-1,4-dione,2,5-bis(1-aziridinyl)-3,6-dipropoxy-

名称

[ CAS 号 ]:
436-40-8

[ 英文名 ]:
2,5-Cyclohexadiene-1,4-dione,2,5-bis(1-aziridinyl)-3,6-dipropoxy-

[英文别名 ]:

Bayer E 39
Cytostaticum
Improcuona [INN-Spanish]
Zytostatika
Inprochonum
Inproquonum [INN-Latin]
Cytostatika
Inproquone
E 39
RP 6870

物理化学性质

[ 分子式 ]:
C₁₆H₂₂N₂O₄

[ 分子量 ]:
306.35700

[ 精确质量 ]:
306.15800

[ PSA ]:
58.62000

[ LogP ]:
0.92160

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DK3327000

CHEMICAL NAME :: p-Benzoquinone, 2,5-bis(1-aziridinyl)-3,6-dipropoxy-

CAS REGISTRY NUMBER :: 436-40-8

BEILSTEIN REFERENCE NO. :: 0286633

LAST UPDATED :: 199612

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C16-H22-N2-O4

MOLECULAR WEIGHT :: 306.40

WISWESSER LINE NOTATION :: T3NTJ A- BL6V DVJ CO3 FO3 E- AT3NTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4300 ug/kg

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea Blood - hemorrhage Nutritional and Gross Metabolic - other changes

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TYPE OF TEST :: Cytogenetic analysis

TYPE OF TEST :: Sister chromatid exchange

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Cells - not otherwise specified

DOSE/DURATION :: 290 nmol/L

REFERENCE :: SOGEBZ Soviet Genetics. English translation of GNKAA5. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.2- 1966- Volume(issue)/page/year: 18,210,1982

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安全信息

[ 海关编码 ]:
2933990090

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海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%