阔叶千里光碱
阔叶千里光碱名称
[ CAS 号 ]:
480-78-4
[ 中文名 ]:
阔叶千里光碱
[ 英文名 ]:
Platyphylline
[中文别名 ]:
[英文别名 ]:
- Platyphylline
- EINECS 207-558-6
阔叶千里光碱物理化学性质
[ 密度 ]:
1.22 g/cm3
[ 沸点 ]:
539.6ºC at 760 mmHg
[ 分子式 ]:
C18H27NO5
[ 分子量 ]:
337.41100
[ 闪点 ]:
280.1ºC
[ 精确质量 ]:
337.18900
[ PSA ]:
76.07000
[ LogP ]:
1.21060
[ 折射率 ]:
1.553
阔叶千里光碱毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TP2518000
- CHEMICAL NAME :
- Platyphylline
- CAS REGISTRY NUMBER :
- 480-78-4
- LAST UPDATED :
- 199801
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C18-H27-N-O5
- MOLECULAR WEIGHT :
- 337.46
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3100 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (1),34,1997
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 252 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AJEBAK Australian Journal of Experimental Biology and Medical Science. (Adelaide, S.A., Australia) V.1-64, 1924-86. Volume(issue)/page/year: 46,493,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - acute pulmonary edema Liver - hepatitis (hepatocellular necrosis), diffuse Blood - lymphoma, including Hodgkin's disease
- REFERENCE :
- RETOAE Research Today. (Indianapolis, IN) V.1-16, 1944-60. Discontinued. Volume(issue)/page/year: 5,53,1949
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2573 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (1),34,1997
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 577 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (1),34,1997
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 105 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - acute pulmonary edema Liver - hepatitis (hepatocellular necrosis), diffuse Blood - lymphoma, including Hodgkin's disease
- REFERENCE :
- RETOAE Research Today. (Indianapolis, IN) V.1-16, 1944-60. Discontinued. Volume(issue)/page/year: 5,53,1949 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5700 mg/kg/19D-I
- TOXIC EFFECTS :
- Liver - liver function tests impaired Related to Chronic Data - death
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (1),34,1997
点击显示
阔叶千里光碱安全信息
[ 危险品运输编码 ]:
UN 1544
[ 包装等级 ]:
III
[ 危险类别 ]:
6.1(b)
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