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9-芴酮

9-芴酮用途

9H-芴-9-酮是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

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9-芴酮名称

[ CAS 号 ]:
486-25-9

[ 中文名 ]:
9-芴酮

[ 英文名 ]:
9-Fluorenone

[中文别名 ]:

[英文别名 ]:

9-Fluorenone
Diphenylene ketone
MFCD00001141
9H-Fluoren-9-one
EINECS 207-630-7
fluoren-9-one
Fluorenone
9-Oxofluorene

9-芴酮生物活性

[ 描述 ]:

9H-芴-9-酮是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

用作有机合成中间体。

9-芴酮物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
341.5±0.0 °C at 760 mmHg

[ 熔点 ]:
80-83 °C(lit.)

[ 分子式 ]:
C₁₃H₈O

[ 分子量 ]:
180.20

[ 闪点 ]:
144.1±13.7 °C

[ 精确质量 ]:
180.057510

[ PSA ]:
17.07000

[ LogP ]:
3.58

[ 外观性状 ]:
黄色结晶粉末

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.667

[ 储存条件 ]:
Store at RT.

[ 稳定性 ]:
Stable. Combustible. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
insoluble

9-芴酮MSDS

详细MSDS(安全技术说明书)

9-芴酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LL8925000

CHEMICAL NAME :: 9H-Fluoren-9-one

CAS REGISTRY NUMBER :: 486-25-9

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C13-H8-O

MOLECULAR WEIGHT :: 180.21

WISWESSER LINE NOTATION :: L B656 HVJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 23,325,1989 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 300 mg/kg/26W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 7,453,1947 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - Z0225 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 28 (estimated)

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9-芴酮安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
LL8925000

[ 包装等级 ]:
II; III

[ 危险类别 ]:
4.1

[ 海关编码 ]:
2914399090

9-芴酮上下游产品

9-芴酮上游产品

9-芴酮下游产品

9-芴酮海关

[ 海关编码 ]: 2914399090

[ 中文概述 ]:
2914399090. 其他不含其他含氧基的芳香酮. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙酮报明包装

[ Summary ]:
2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

9-芴酮文献

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Indoleamine 2,3-dioxygenase (IDO) is an important therapeutic target for the treatment of diseases such as cancer that involve pathological immune escape. We have used the evolutionary docking algorit...

Photosensitizing properties of compounds related to benzophenone.

Acta Derm. Venereol. 93(1) , 30-2, (2013)

Benzophenone is a phototoxic compound with absorption maxima in the ultraviolet A (UVA) and ultraviolet B (UVB) range. Many benzophenone derivatives are known to be photosensitizing. On the other hand...

Broad spectrum analysis of polar and apolar organic compounds in submicron atmospheric particles.

J. Chromatogr. A. 1404 , 28-38, (2015)

A method for the quantitative analysis of organic compounds on submicron particulate matter (PM1) collected on quartz filters was developed. The compounds analyzed encompassed C22-C35 alkanes, polycyc...

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