次氮基三乙酸钠盐
次氮基三乙酸钠盐用途
次氮基三乙酸钠盐名称
[ CAS 号 ]:
5064-31-3
[ 中文名 ]:
次氮基三乙酸钠盐
[ 英文名 ]:
SODIUM NITRILOTRIACETATE
[中文别名 ]:
[英文别名 ]:
- EINECS 225-768-6
- SODIUM NITRILOTRIACETATE
- trisodium,2-[bis(carboxylatomethyl)amino]acetate
- Nitrilotriacetic acid trisodium salt
- MFCD00064231
- Monosodium nitrilotriacetate
- Trisodium nitrilotriacetate
- Trisodium 2,2',2''-nitrilotriacetate
- NTA-3Na
次氮基三乙酸钠盐生物活性
次氮基三乙酸钠盐物理化学性质
[ 密度 ]:
0.56
[ 沸点 ]:
498.2ºC at 760mmHg
[ 熔点 ]:
69-71 °C(lit.)
[ 分子式 ]:
C6H6NNa3O6
[ 分子量 ]:
257.084
[ 闪点 ]:
255.1ºC
[ 精确质量 ]:
256.988831
[ PSA ]:
123.63000
[ 外观性状 ]:
透明稻黄色的液体
[ 储存条件 ]:
室温,干燥
[ 水溶解性 ]:
insoluble
次氮基三乙酸钠盐MSDS
次氮基三乙酸钠盐毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MB8400000
- CHEMICAL NAME :
- Glycine, N,N-bis(carboxymethyl)-, trisodium salt
- CAS REGISTRY NUMBER :
- 5064-31-3
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 25
- MOLECULAR FORMULA :
- C6-H6-N-O6.3Na
- MOLECULAR WEIGHT :
- 257.10
- WISWESSER LINE NOTATION :
- QV1N1VQ1VQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1100 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 254 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 681 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 180 gm/kg/90D-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in erythrocyte (RBC) count
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 56305 mg/kg/30D-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 219 gm/kg/2Y-C
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes in urine composition Nutritional and Gross Metabolic - changes in metals, not otherwise specified Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 70300 mg/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 39 gm/kg
- SEX/DURATION :
- male 8 week(s) pre-mating female 8 week(s) pre-mating - 3 week(s) post-birth
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 8 gm/kg
- SEX/DURATION :
- male 8 week(s) pre-mating female 8 week(s) pre-mating - 3 week(s) post-birth
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- TYPE OF TEST :
- Specific locus test
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 3 mmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 343,1,1995 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 48,181,1990 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 48,181,1990 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M0951 No. of Facilities: 7988 (estimated) No. of Industries: 82 No. of Occupations: 64 No. of Employees: 77882 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M0951 No. of Facilities: 11433 (estimated) No. of Industries: 95 No. of Occupations: 97 No. of Employees: 224263 (estimated) No. of Female Employees: 60818 (estimated)
次氮基三乙酸钠盐安全信息
[ 符号 ]:
GHS07, GHS08
[ 信号词 ]:
Warning
[ 危害声明 ]:
H302-H319-H351
[ 警示性声明 ]:
P301 + P312 + P330-P305 + P351 + P338
[ 个人防护装备 ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ 危害码 (欧洲) ]:
Xn
[ 风险声明 (欧洲) ]:
R22
[ 安全声明 (欧洲) ]:
S36
[ 危险品运输编码 ]:
NONH for all modes of transport
[ WGK德国 ]:
2
[ RTECS号 ]:
MB8400000
[ 海关编码 ]:
2921199090
次氮基三乙酸钠盐海关
[ 海关编码 ]: 2921199090
[ 中文概述 ]:
2921199090 其他无环单胺及其衍生物及其盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
次氮基三乙酸钠盐文献
Appl. Environ. Microbiol. 81(7) , 2274-83, (2015)
Bacillus cereus is an opportunistic human pathogen responsible for food poisoning and other, nongastrointestinal infections. Due to the emergence of multidrug-resistant B. cereus strains, the demand f...
Gel scaffolds of BMP-2-binding peptide amphiphile nanofibers for spinal arthrodesis.Adv. Healthc. Mater. 4(1) , 131-41, (2015)
Peptide amphiphile (PA) nanofibers formed by self-assembly can be customized for specific applications in regenerative medicine through the use of molecules that display bioactive signals on their sur...
An integrated biological approach to guide the development of metal-chelating inhibitors of influenza virus PA endonuclease.Mol. Pharmacol. 87(2) , 323-37, (2015)
The influenza virus PA endonuclease, which cleaves capped cellular pre-mRNAs to prime viral mRNA synthesis, is a promising target for novel anti-influenza virus therapeutics. The catalytic center of t...
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