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1-氯乙基碳酸乙酯

1-氯乙基碳酸乙酯用途

【用途一】
用作坎地沙坦酯、头孢替安酯等药物中间体

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1-氯乙基碳酸乙酯名称

[ CAS 号 ]:
50893-36-2

[ 中文名 ]:
1-氯乙基乙基碳酸酯

[ 英文名 ]:
1-Chloroethyl ethyl carbonate

[中文别名 ]:

[英文别名 ]:

1-chloroethy ethyl carbonate
1-Ethoxycarbonyloxyethyl chloride
1-Chloroethylethylcarbonate
1-Chlorodiethyl Carbonate
Carbonic Acid 1-Chloroethyl Ethyl Ester
Carbonic acid, 1-chloroethyl ethyl ester
Carbonic acid ethyl 1-chloroethyl ester
EINECS 256-832-1
1-Chloroethyl ethyl carbonate
MFCD00040523

1-氯乙基碳酸乙酯物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
147.5±23.0 °C at 760 mmHg

[ 熔点 ]:
159-161°C

[ 分子式 ]:
C₅H₉ClO₃

[ 分子量 ]:
152.576

[ 闪点 ]:
50.0±21.6 °C

[ 精确质量 ]:
152.024017

[ PSA ]:
35.53000

[ LogP ]:
1.26

[ 外观性状 ]:
液体;Colorless to Light yellow clear liquid

[ 蒸汽压 ]:
4.4±0.3 mmHg at 25°C

[ 折射率 ]:
1.420

[ 储存条件 ]:
2-8°C

1-氯乙基碳酸乙酯MSDS

1-氯乙基碳酸乙酯安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S28

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2920909090

1-氯乙基碳酸乙酯合成路线

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1-氯乙基碳酸乙酯海关

[ 海关编码 ]: 2920909090

[ 中文概述 ]:
2920909090 其他无机酸酯（不包括卤化氢的酯）（包括其盐及它们的卤化，磺化，硝化和亚硝化衍生物）。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2920909090 esters of other inorganic acids of non-metals (excluding esters of hydrogen halides) and their salts; their halogenated, sulphonated, nitrated or nitrosated derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

1-氯乙基碳酸乙酯文献

Tranexamic acid derivatives with enhanced absorption.

J. Med. Chem. 29 , 448, (1986)

Derivatives of the antifibrinolytic drug tranexamic acid [trans-4-(aminomethyl)cyclohexanecarboxylic acid] containing one or two tranexamic acid moieties were synthesized. Most of the derivatives have...

Orally active 1-(cyclohexyloxycarbonyloxy)alkyl ester prodrugs of cefotiam.

J. Antibiot. 40 , 81, (1987)

Orally active 1-(alkyl substituted cyclohexyloxycarbonyloxy)alkyl ester prodrugs (9b-h) of 7 beta-[2-(2-aminothiazol-4-yl)acetamido]-3- [[[1-(2-dimethylaminoethyl)-1H-tetrazol-5-yl]thio]-methyl]ceph+ ...

G. Barcelo et al.

Synthesis , 627, (1986)

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