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4-氟-DL-苯丙氨酸

4-氟-DL-苯丙氨酸用途

2-氨基-3-(4-氟苯基)丙酸是苯丙氨酸衍生物[1]。

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4-氟-DL-苯丙氨酸名称

[ CAS 号 ]:
51-65-0

[ 中文名 ]:
DL-对氟苯丙氨酸

[ 英文名 ]:
4-Fluoro-L-phenylalanine

[中文别名 ]:

[英文别名 ]:

EINECS 200-113-7
p-Fluoro-DL-phenylalanine
S-(-)-p-Fluorophenylalanine
para-fluorophenylalanine
4-Fluorophenylalanine
DL-4-Fluorophenylalanine
4-Fluoro-DL-.β.-phenylalanine
L-4-Fluorophenylalanine
p-Fluoro-L-phenylalanine
L-4-Fluoro-Phenylalanine

4-氟-DL-苯丙氨酸生物活性

[ 描述 ]:

2-氨基-3-(4-氟苯基)丙酸是苯丙氨酸衍生物[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。

[参考文献]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-814.

4-氟-DL-苯丙氨酸物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
313.3±32.0 °C at 760 mmHg

[ 熔点 ]:
253-255ºC

[ 分子式 ]:
C₉H₁₀FNO₂

[ 分子量 ]:
183.180

[ 闪点 ]:
143.3±25.1 °C

[ 精确质量 ]:
183.069550

[ PSA ]:
63.32000

[ LogP ]:
1.16

[ 外观性状 ]:
白色粉末或白色有光泽的片

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.555

[ 储存条件 ]:
室温，密封，干燥

[ 稳定性 ]:
Stable. Combustible. Incompatible with strong oxidising agents. May be light sensitive.

[ 水溶解性 ]:
slightly soluble

4-氟-DL-苯丙氨酸MSDS

详细MSDS(安全技术说明书)

4-氟-DL-苯丙氨酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AY6315000

CHEMICAL NAME :: Alanine, 3-(p-fluorophenyl)-, DL-

CAS REGISTRY NUMBER :: 51-65-0

LAST UPDATED :: 199701

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C9-H10-F-N-O2

MOLECULAR WEIGHT :: 183.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Rodent - rabbit Kidney

DOSE/DURATION :: 500 umol/L

REFERENCE :: ECREAL Experimental Cell Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.10- 1950- Volume(issue)/page/year: 36,92,1964

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4-氟-DL-苯丙氨酸安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H300

[ 警示性声明 ]:
P264-P301 + P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T:Toxic;

[ 风险声明 (欧洲) ]:
R25

[ 安全声明 (欧洲) ]:
S45

[ 危险品运输编码 ]:
UN 2811

[ WGK德国 ]:
3

[ RTECS号 ]:
AY6315000

[ 包装等级 ]:
III

[ 海关编码 ]:
2922499990

4-氟-DL-苯丙氨酸上下游产品

4-氟-DL-苯丙氨酸上游产品

4-氟-DL-苯丙氨酸下游产品

4-氟-DL-苯丙氨酸制备

【方法一】
以对氟苯甲醛和马尿酸为原料反应得粗品，然后经纯化精制得产品

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4-氟-DL-苯丙氨酸海关

[ 海关编码 ]: 2922499990

[ 中文概述 ]:
2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

4-氟-DL-苯丙氨酸文献

Determination of homocysteine in cerebrospinal fluid as an indicator for surgery treatment in patients with hydrocefalus.

Physiol. Res. 63(4) , 521-7, (2014)

Increased homocysteine levels in serum are typical features of neurodegenerative brain diseases including hydrocephalus. The most frequent therapeutic approach consists of the insertion of a shunt, co...

Simultaneous determination of gabapentin, pregabalin, vigabatrin, and topiramate in plasma by HPLC with fluorescence detection.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 962 , 82-8, (2014)

Therapeutic drug monitoring (TDM) of antiepileptic drugs (AEDs) has been recognized as a useful tool in management of epilepsy. We developed a simple analytical method for simultaneous determination o...

Studies on the inhibition of Moloney murine leukemia virus reverse transcriptase by N-tritylamino acids and N-tritylamino acid-nucleotide compounds.

Nucleosides Nucleotides Nucleic Acids 27 , 1011-1023, (2008)

N-Acylated derivatives of 8-(6-aminohexyl) amino-adenosine-5 '-phosphate were prepared and studied with regard to their effect on DNA synthesis by the Moloney leukemia virus reverse transcriptase. N-p...

更多文献

4-氟-DL-苯丙氨酸

4-氟-DL-苯丙氨酸用途

4-氟-DL-苯丙氨酸名称

4-氟-DL-苯丙氨酸生物活性

4-氟-DL-苯丙氨酸物理化学性质

4-氟-DL-苯丙氨酸MSDS

详细MSDS(安全技术说明书)

4-氟-DL-苯丙氨酸毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

4-氟-DL-苯丙氨酸安全信息

4-氟-DL-苯丙氨酸上下游产品

4-氟-DL-苯丙氨酸上游产品

4-氟-DL-苯丙氨酸下游产品

4-氟-DL-苯丙氨酸制备

4-氟-DL-苯丙氨酸海关

4-氟-DL-苯丙氨酸文献

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