2H-1,3,2-Oxazaphosphorin-2-amine,N,N-diethyltetrahydro-, 2-oxide

名称

[ CAS 号 ]:
53859-37-3

[ 英文名 ]:
2H-1,3,2-Oxazaphosphorin-2-amine,N,N-diethyltetrahydro-, 2-oxide

[英文别名 ]:

Dechlorcyclophosphamide
B 516
N,N-Diethylcyclophosphamide
Didechlorocyclophosphamide
ASTA 7019
n,n-diethyl-1,3,2-oxazaphosphinan-2-amine 2-oxide
ASTA B 516

物理化学性质

[ 密度 ]:
1.11g/cm3

[ 沸点 ]:
249ºC at 760mmHg

[ 分子式 ]:
C₇H₁₇N₂O₂P

[ 分子量 ]:
192.19600

[ 闪点 ]:
104.4ºC

[ 精确质量 ]:
192.10300

[ PSA ]:
51.38000

[ LogP ]:
1.77500

[ 折射率 ]:
1.473

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RP5788700

CHEMICAL NAME :: 2H-1,3,2-Oxazaphosphorin-2-amine, tetrahydro-N,N-diethyl-, 2-oxide

CAS REGISTRY NUMBER :: 53859-37-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C7-H17-N2-O2-P

MOLECULAR WEIGHT :: 192.23

WISWESSER LINE NOTATION :: T6MPOTJ BO BN2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Bird - chicken Cells - not otherwise specified

DOSE/DURATION :: 211 mg/kg

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 268,115,1992

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安全信息

[ 海关编码 ]:
2934999090

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[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%