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4-(二甲氨基)-2-甲基偶氮苯

4-(二甲氨基)-2-甲基偶氮苯名称

[ CAS 号 ]:
54-88-6

[ 中文名 ]:
4-二甲氨基-2-甲基偶氮苯

[ 英文名 ]:
4-dimethylamino-2-methylazobenzene

[中文别名 ]:

[英文别名 ]:

N,N,3-trimethyl-4-(phenylazo)-benzenamine
2-methyl-4-dimethylaminoazobenzene
2-MethylDAB
6-Benzolazo-3-dimethylamino-touol
N,N-Dimethyl-4-phenylazo-m-toluidine
3,N,N-Trimethyl-4-phenylazo-anilin
4-N,N-Dimethylamino-2-methylazobenzene
3,N,N-trimethyl-4-phenylazo-aniline
MFCD00008306
EINECS 200-217-2

4-(二甲氨基)-2-甲基偶氮苯物理化学性质

[ 密度 ]:
1.01g/cm3

[ 沸点 ]:
150ºC / 16mmHg

[ 熔点 ]:
67-69ºC(lit.)

[ 分子式 ]:
C₁₅H₁₇N₃

[ 分子量 ]:
239.31600

[ 闪点 ]:
190.2ºC

[ 精确质量 ]:
239.14200

[ PSA ]:
27.96000

[ LogP ]:
4.47640

[ 外观性状 ]:
橙色结晶固体

[ 折射率 ]:
1.561

[ 储存条件 ]:
室温

[ 水溶解性 ]:
Solubility Practically insoluble in water; soluble in ethanol, acetone

4-(二甲氨基)-2-甲基偶氮苯MSDS

4-(二甲氨基)-2-甲基偶氮苯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XU5950000

CHEMICAL NAME :: m-Toluidine, N,N-dimethyl-4-(phenylazo)-

CAS REGISTRY NUMBER :: 54-88-6

LAST UPDATED :: 199707

DATA ITEMS CITED :: 21

MOLECULAR FORMULA :: C15-H17-N3

MOLECULAR WEIGHT :: 239.35

WISWESSER LINE NOTATION :: 1N1&R C1 DNUNR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 345 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 40 mg/kg/5D-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors

TYPE OF TEST :: DNA adduct

TYPE OF TEST :: Mutation test systems - not otherwise specified

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Fibroblast

DOSE/DURATION :: 40 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 93,409,1982

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4-(二甲氨基)-2-甲基偶氮苯安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H351-H413

[ 警示性声明 ]:
P281

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
R23/24;R33

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
XU5950000

[ 海关编码 ]:
2927000090

4-(二甲氨基)-2-甲基偶氮苯合成路线

4-(二甲氨基)-2-甲基偶氮苯上下游产品

4-(二甲氨基)-2-甲基偶氮苯上游产品

4-(二甲氨基)-2-甲基偶氮苯下游产品

4-(二甲氨基)-2-甲基偶氮苯海关

[ 海关编码 ]: 2927000090

[ 中文概述 ]:
2927000090 其他重氮化合物、偶氮化合物等（包括氧化偶氮化合物）. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

4-(二甲氨基)-2-甲基偶氮苯文献

Inhibition of mitochondrial electron transport and energy transduction by 2-methyl-4-dimethylaminoazobenzene in vitro.

Indian J. Biochem. Biophys. 21(5) , 309-13, (1984)

Toxic effects of 2-methyl-4-dimethylaminoazobenzene in normal and partially hepatectomized rats.

Chem. Biol. Interact. 48(2) , 221-35, (1984)

In order to obtain a more precise definition of the conditions under which 2-methyl-4-dimethylaminoazobenzene (2-Me-DAB) and liver cell proliferation play a role in the initiation of hepatocarcinogene...

The effect of carcinogens on the accumulation of tyrosine aminotransferase by foetal rat hepatocytes in culture.

Eur. J. Cancer Clin. Oncol. 18(11) , 1163-70, (1982)

The hepatocarcinogen 3'-methyl-4-dimethyl-aminoazobenzene (MDAB) suppresses the accumulation of tyrosine aminotransferase in cultured foetal hepatocytes. Experiments involving liver derived from foetu...

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