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硫代乙醇酸铵

硫代乙醇酸铵用途

【用途一】
用于测定铁的试剂及制药工业
【用途二】
在化妆品中用作卷发剂、营养液，起定型作用
【用途三】
光度试剂和掩蔽剂。测定铁、铝、银和锡等离子。卷发冷烫剂。

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硫代乙醇酸铵名称

[ CAS 号 ]:
5421-46-5

[ 中文名 ]:
巯基乙酸铵

[ 英文名 ]:
Ammonium thioglycolate

[中文别名 ]:

[英文别名 ]:

azanium,2-sulfanylacetate
MFCD00137451
EINECS 226-540-9

硫代乙醇酸铵物理化学性质

[ 密度 ]:
1.311g/cm3

[ 沸点 ]:
115ºC

[ 熔点 ]:
-10ºC

[ 分子式 ]:
C₂H₇NO₂S

[ 分子量 ]:
109.14700

[ 闪点 ]:
99.8ºC

[ 精确质量 ]:
109.02000

[ PSA ]:
78.93000

[ 外观性状 ]:
无色至淡的粉红色液体

[ 储存条件 ]:
库房通风低温干燥

[ 水溶解性 ]:
Miscible

硫代乙醇酸铵MSDS

详细MSDS(安全技术说明书)

硫代乙醇酸铵毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AI7525000

CHEMICAL NAME :: Acetic acid, mercapto-, monoammonium salt

CAS REGISTRY NUMBER :: 5421-46-5

LAST UPDATED :: 199712

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C2-H4-O2-S.H3-N

MOLECULAR WEIGHT :: 109.16

WISWESSER LINE NOTATION :: SH1VO &ZH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 165 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 97,349,1949

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 175 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 97,349,1949

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 97,349,1949 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83494 No. of Facilities: 4049 (estimated) No. of Industries: 4 No. of Occupations: 3 No. of Employees: 33142 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83494 No. of Facilities: 4016 (estimated) No. of Industries: 6 No. of Occupations: 5 No. of Employees: 41131 (estimated) No. of Female Employees: 30870 (estimated)

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硫代乙醇酸铵安全信息

[ 符号 ]:

GHS05, GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H290-H301-H317

[ 警示性声明 ]:
P280-P301 + P310

[ 个人防护装备 ]:
Eyeshields;Gloves

[ 危害码 (欧洲) ]:
T

[ 风险声明 (欧洲) ]:
25-43

[ 安全声明 (欧洲) ]:
36/37-45

[ 危险品运输编码 ]:
2810

[ WGK德国 ]:
1

[ RTECS号 ]:
AI7525000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

硫代乙醇酸铵制备

1.主要采用中和法。以巯代乙醇酸和碳酸氢铵为原料，进行中和反应，然后经过滤而得。也可以氯乙酸、硫脲和氢氧化钡为原料制得硫代乙醇酸钡，再与铵盐反应而得。

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硫代乙醇酸铵文献

Mercaptoacetate and fatty acids exert direct and antagonistic effects on nodose neurons via GPR40 fatty acid receptors.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 307(1) , R35-43, (2014)

β-mercaptoacetate (MA) is a drug known to block mitochondrial oxidation of medium- and long-chain fatty acids (FAs) and to stimulate feeding. Because MA-induced feeding is vagally dependent, it has be...

Preactivated thiomers for vaginal drug delivery vehicles.

Biomaterials 34(32) , 7811-8, (2013)

It was the purpose of this study to design and evaluate a chitosan derivative as mucoadhesive excipient for vaginal drug delivery systems. The chemical modification of chitosan was achieved by conjuga...

更多文献

硫代乙醇酸铵

硫代乙醇酸铵用途

硫代乙醇酸铵名称

硫代乙醇酸铵物理化学性质

硫代乙醇酸铵MSDS

详细MSDS(安全技术说明书)

硫代乙醇酸铵毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

硫代乙醇酸铵安全信息

硫代乙醇酸铵制备

硫代乙醇酸铵文献

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