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2,4-二氯-6-甲基嘧啶

2,4-二氯-6-甲基嘧啶用途

作为医药中间体

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2,4-二氯-6-甲基嘧啶名称

[ CAS 号 ]:
5424-21-5

[ 中文名 ]:
2,4-二氯-6-甲基嘧啶

[ 英文名 ]:
2,4-Dichloro-6-methylpyrimidine

[中文别名 ]:

[英文别名 ]:

2,4-dichloro-6-methyl pyrimidine
2,4,5-TRIFLUOROBENZAMIDINE HYDROCHLORIDE
2,4-dichloro-6-methyl-pyrimidine
EINECS 226-563-4
2,4-Dichloro-6-methylpyrimidine
Pyrimidine,2,4-dichloro-6-methyl
MFCD00006064
Pyrimidine, 2,4-dichloro-6-methyl-
2,6-dichloro-4-methylpyrimidine
6-methyl-2,4-dichloropyrimidine

2,4-二氯-6-甲基嘧啶物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
219.0±20.0 °C at 760 mmHg

[ 熔点 ]:
44-47 °C(lit.)

[ 分子式 ]:
C₅H₄Cl₂N₂

[ 分子量 ]:
163.005

[ 闪点 ]:
107.0±7.4 °C

[ 精确质量 ]:
161.975159

[ PSA ]:
25.78000

[ LogP ]:
1.62

[ 外观性状 ]:
淡黄色棱柱晶体

[ 蒸汽压 ]:
0.2±0.4 mmHg at 25°C

[ 折射率 ]:
1.551

[ 储存条件 ]:
存放于惰性气体之中;避免空气

2,4-二氯-6-甲基嘧啶MSDS

2,4-二氯-6-甲基嘧啶安全信息

[ 符号 ]:

GHS05

[ 信号词 ]:
Danger

[ 危害声明 ]:
H314

[ 警示性声明 ]:
P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
C:Corrosive;

[ 风险声明 (欧洲) ]:
R34

[ 安全声明 (欧洲) ]:
S26-S27-S36/37/39-S45

[ 危险品运输编码 ]:
UN 3263 8/PG 2

[ WGK德国 ]:
3

[ 包装等级 ]:
III

[ 危险类别 ]:
8

[ 海关编码 ]:
2933599090

2,4-二氯-6-甲基嘧啶合成路线

2,4-二氯-6-甲基嘧啶上下游产品

2,4-二氯-6-甲基嘧啶上游产品

2,4-二氯-6-甲基嘧啶下游产品

2,4-二氯-6-甲基嘧啶海关

[ 海关编码 ]: 2933599090

[ 中文概述 ]:
2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2,4-二氯-6-甲基嘧啶文献

4-Arylvinyl-2,6-di(pyridin-2-yl)pyrimidines: synthesis and optical properties.

J. Org. Chem. 76(10) , 3837-45, (2011)

A series of 4-arylvinyl-2,6-di(pyridin-2-yl)pyrimidines have been efficiently prepared by a double cross-coupling reaction between 2,4-dichloro-6-methylpyrimidine and 2-(tributylstannyl)pyridine, foll...

Fluorous synthesis of disubstituted pyrimidines.

Org. Lett. 5(7) , 1011-3, (2003)

[reaction: see text] The fluorous synthesis of disubstituted pyrimidines is carried out by attaching 2,4-dichloro-6-methylpyrimidine with 1H,1H,2H,2H-perfluorodecanethiol. The tagged substrate is subs...

Novel inhibitors of Rac1 in metastatic breast cancer.

P. R. Health Sci. J. 29(4) , 348-56, (2010)

Rho family GTPases are molecular switches that control signaling pathways regulating a myriad of cellular functions. Rac1, a Rho family member, plays a critical role in several aspects of tumorigenesi...

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