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1-苯基双胍盐酸盐

1-苯基双胍盐酸盐名称

[ CAS 号 ]:
55-57-2

[ 中文名 ]:
1-苯基双胍盐酸盐

[ 英文名 ]:
1-phenylbiguanide hydrochloride

[中文别名 ]:

1-苯基双胍盐酸盐

[英文别名 ]:

Phenylbiguanide monohydrochloride
Phenylbiguanide hydrochloride
1-phenylbiguanide hydrochloride
MFCD00035040
N-phenylbiguanide hydrochloride
Phenyldiguanide hydrochloride
EINECS 200-239-2
N'-Phenylbiguanide monohydrochloride
N-phenylimidodicarbonimidic diamide hydrochloride
1-Phenylbiquanide hydrochloride

1-苯基双胍盐酸盐物理化学性质

[ 密度 ]:
1.33g/cm3

[ 沸点 ]:
388.4ºC at 760mmHg

[ 熔点 ]:
244-247ºC(lit.)

[ 分子式 ]:
C₈H₁₂ClN₅

[ 分子量 ]:
213.66700

[ 闪点 ]:
188.7ºC

[ 精确质量 ]:
213.07800

[ PSA ]:
97.78000

[ LogP ]:
2.68200

[ 储存条件 ]:
Store at RT

1-苯基双胍盐酸盐MSDS

1-苯基双胍盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DU2550000

CHEMICAL NAME :: Biguanide, 1-phenyl-, monohydrochloride

CAS REGISTRY NUMBER :: 55-57-2

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C8-H11-N5.Cl-H

MOLECULAR WEIGHT :: 213.70

WISWESSER LINE NOTATION :: MUYZMYUM&MR &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CKFRAY Ceskoslovenska Farmacie. (PNS-Ustredni Expedice a Dovoz Tisku, Kafkova 19, 160 00 Prague 6, Czechoslovakia) V.1- 1952- Volume(issue)/page/year: 1,434,1952

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 243 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PLRCAT Pharmacological Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year: 6,117,1974

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1-苯基双胍盐酸盐安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
DU2550000

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1-苯基双胍盐酸盐文献

Indian red scorpion venom-induced augmentation of cardio-respiratory reflexes and pulmonary edema involve the release of histamine.

Toxicon 57(2) , 193-8, (2011)

Pulmonary edema is a consistent feature of Mesobuthus tamulus (MBT) envenomation. Kinins, prostaglandins and other inflammatory mediators are implicated in it. Since, histamine also increases capillar...

Effect of 3,5-dicarbomethoxyphenylbiguanide on free radical homeostasis in rats with experimental myocarditis.

Bull. Exp. Biol. Med. 154(2) , 192-5, (2012)

Administration of 3,5-dicarbomethoxyphenylbiguanide to rats with experimental epinephrine-induced myocarditis was followed by a decrease in activity of marker enzymes for cardiomyocyte cytolysis in th...

B(2) kinin receptors mediate the Indian red scorpion venom-induced augmentation of visceral reflexes via the nitric oxide cyclic guanosine monophosphate pathway.

Acta Physiol. (Oxf.) 196(4) , 365-73, (2009)

This study was performed to delineate the kinin (receptor)-dependent pathways in the Indian red scorpion (Mesobuthus tamulus; MBT) venom-induced pulmonary oedema as well as the augmentation of cardio-...

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