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阿米美啶

阿米美啶用途

Amisometradine is a diuretic which may be used in the treatment of congestive heart failure.

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阿米美啶名称

[ CAS 号 ]:
550-28-7

[ 中文名 ]:
阿米美啶

[ 英文名 ]:
Amisometradine

[英文别名 ]:

Aminoisometradin
6-Amino-1-metallyl-3-methylpyrimidine-2,4-dione
AMISOMETRADINE
Aminoisometradine
Amisometradin
Rolicton
6-Amino-1-methallyl-3-methyl-1H-pyrimidin-2,4-dion
Amisometradinum [INN-Latin]
6-Amino-3-methyl-1-(2-methylallyl)uracil
Uracil,6-amino-3-methyl-1-(2-methylallyl)

阿米美啶物理化学性质

[ 密度 ]:
1.176g/cm3

[ 沸点 ]:
292.1ºC at 760 mmHg

[ 分子式 ]:
C₉H₁₃N₃O₂

[ 分子量 ]:
195.21800

[ 闪点 ]:
130.5ºC

[ 精确质量 ]:
195.10100

[ PSA ]:
70.02000

[ LogP ]:
0.28650

[ 折射率 ]:
1.537

[ 储存条件 ]:
库房通风低温干燥

阿米美啶毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YQ8800000

CHEMICAL NAME :: Uracil, 6-amino-3-methyl-1-(2-methylallyl)-

CAS REGISTRY NUMBER :: 550-28-7

BEILSTEIN REFERENCE NO. :: 0182347

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C9-H13-N3-O2

MOLECULAR WEIGHT :: 195.25

WISWESSER LINE NOTATION :: T6NVNVJ A1Y1&U1 C1 FZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1560 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 126,400,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 515 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 126,400,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 610 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,79,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 415 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,79,1989

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阿米美啶安全信息

[ 海关编码 ]:
2933599090

阿米美啶合成路线

详细合成路线

阿米美啶上下游产品

阿米美啶上游产品

阿米美啶下游产品

阿米美啶海关

[ 海关编码 ]: 2933599090

[ 中文概述 ]:
2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%