脱氧卡巴氧

脱氧卡巴氧用途

Desoxycarbadox 是 Carbadox (HY-B1340) 的代谢产物。Carbadox 是一种喹喔啉二氮氧化物抗生素化合物。

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脱氧卡巴氧名称

[ CAS 号 ]:
55456-55-8

[ 中文名 ]:
脱氧卡巴氧/脱氧卡巴多司

[ 英文名 ]:
Desoxycarbadox

[英文别名 ]:

N,N'-Desoxycarbadox
Desoxycarbadox
Carbadox,deoxy

脱氧卡巴氧生物活性

[ 描述 ]:

Desoxycarbadox 是 Carbadox (HY-B1340) 的代谢产物。Carbadox 是一种喹喔啉二氮氧化物抗生素化合物。

[ 相关类别 ]:

研究领域 >> 癌症

信号通路 >> 其他 >> 其他

[体内研究]

去氧卡巴多在大鼠体内的致瘤活性中起重要作用[3]。

[参考文献]

[1]. MacIntosh AI, et al. Liquid chromatographic monitoring of the depletion of carbadox and its metabolite desoxycarbadox in swine tissues. J Assoc Off Anal Chem. 1985;68(4):665-671.

[2]. Looft T, et al. Carbadox has both temporary and lasting effects on the swine gut microbiota. Front Microbiol. 2014;5:276. Published 2014 Jun 10.

[3]. Zhang K, et al. Investigation of quinocetone-induced mitochondrial damage and apoptosis in HepG2 cells and compared with its metabolites. Environ Toxicol Pharmacol. 2015;39(2):555-567.

脱氧卡巴氧物理化学性质

[ 密度 ]:
1.32g/cm3

[ 分子式 ]:
C₁₁H₁₀N₄O₂

[ 分子量 ]:
230.22300

[ 精确质量 ]:
230.08000

[ PSA ]:
79.96000

[ LogP ]:
1.52410

[ 折射率 ]:
1.634

[ 储存条件 ]:
室温

脱氧卡巴氧MSDS

详细MSDS(安全技术说明书)

脱氧卡巴氧安全信息

[ 符号 ]:

GHS02, GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H228-H302-H350

[ 警示性声明 ]:
P201-P210-P308 + P313

[ 危害码 (欧洲) ]:
F,T

[ 风险声明 (欧洲) ]:
45-11-22

[ 安全声明 (欧洲) ]:
53-45

[ 危险品运输编码 ]:
UN1325 - class 4.1 - PG 2 - Flammable solids, organic, n.o.s., HI: all

脱氧卡巴氧文献

Residues of carbadox metabolites in edible pork products.

Arch. Toxicol. Suppl. 14 , 288-92, (1991)

Liquid chromatographic determination of carbadox, desoxycarbadox, and nitrofurazones in pork tissues.

J. Assoc. Off. Anal. Chem. 67(5) , 958-62, (1984)

A liquid chromatographic (LC) method has been developed for the determination of carbadox, desoxycarbadox, and nitrofurazones in the 10-40 ppb range in pork muscle, liver, and kidney tissues. Tissues ...

Liquid chromatographic determination of carbadox and desoxycarbadox in medicated feeds and in porcine gastrointestinal tract.

J. Assoc. Off. Anal. Chem. 68(4) , 658-60, (1985)

A liquid chromatographic method for the assay of carbadox and desoxycarbadox in medicated feeds and porcine stomach and intestinal contents is described. Samples were extracted with dimethylformamide-...

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