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美托洛尔酸

美托洛尔酸用途

Metoprolol acid is a pharmacologically inactive urinary metoprolol metabolite.
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美托洛尔酸名称

[ CAS 号 ]:
56392-14-4

[ 中文名 ]:
美特洛尔

[ 英文名 ]:
Metoprolol Acid

[中文别名 ]:

[英文别名 ]:

美托洛尔酸物理化学性质

[ 密度 ]:
1.159g/cm3

[ 沸点 ]:
477.1ºC at 760mmHg

[ 熔点 ]:
174-176ºC

[ 分子式 ]:
C14H21NO4

[ 分子量 ]:
267.32100

[ 闪点 ]:
242.3ºC

[ 精确质量 ]:
267.14700

[ PSA ]:
78.79000

[ LogP ]:
1.44230

[ 折射率 ]:
1.539

[ 储存条件 ]:
-20°C

美托洛尔酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CY1634360
CHEMICAL NAME :
Benzeneacetic acid, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-
CAS REGISTRY NUMBER :
56392-14-4
LAST UPDATED :
199110
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H21-N-O4
MOLECULAR WEIGHT :
267.36

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PBPSDY Pharmacological and Biochemical Properties of Drug Substances. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.1- 1977- Volume(issue)/page/year: 2,186,1979
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美托洛尔酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
CY1634360

美托洛尔酸文献

The impact of different proportions of a treated effluent on the biotransformation of selected micro-contaminants in river water microcosms.

Int. J. Environ. Res. Public Health 11(10) , 10390-405, (2014)

Attenuation of micro-contaminants is a very complex field in environmental science and evidence suggests that biodegradation rates of micro-contaminants in the aqueous environment depend on the water ...

Pregnancy-induced increase in metoprolol metabolism.

Clin. Pharmacol. Ther. 37(6) , 688-92, (1985)

Five women who developed hypertension during pregnancy received metoprolol, 10 mg iv; 3 days later they received metoprolol, 100 mg by mouth. Blood and urine samples were collected after each dose. Th...

Determination of two metoprolol metabolites in human urine by high-performance liquid chromatography.

J. Chromatogr. A. 309(1) , 198-202, (1984)


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公司名:上海化源世纪贸易有限公司

区域:上海市普陀区

价格:

联系人:徐经理

产品详情:美托洛尔酸


公司名:上海阿拉丁生化科技股份有限公司

区域:上海市浦东新区

价格:
¥1999.9/10mg ¥需询单/1g ¥需询单/1g ¥需询单/1g

联系人:阿拉丁

产品详情:美托洛尔酸


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