美托洛尔酸
美托洛尔酸用途
美托洛尔酸名称
[ CAS 号 ]:
56392-14-4
[ 中文名 ]:
美特洛尔
[ 英文名 ]:
Metoprolol Acid
[中文别名 ]:
[英文别名 ]:
- Metoprolol acid
- SL 77-010
- H 117/04
- Atenolol acid
- Atenolol Impurity 7
美托洛尔酸物理化学性质
[ 密度 ]:
1.159g/cm3
[ 沸点 ]:
477.1ºC at 760mmHg
[ 熔点 ]:
174-176ºC
[ 分子式 ]:
C14H21NO4
[ 分子量 ]:
267.32100
[ 闪点 ]:
242.3ºC
[ 精确质量 ]:
267.14700
[ PSA ]:
78.79000
[ LogP ]:
1.44230
[ 折射率 ]:
1.539
[ 储存条件 ]:
-20°C
美托洛尔酸毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CY1634360
- CHEMICAL NAME :
- Benzeneacetic acid, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-
- CAS REGISTRY NUMBER :
- 56392-14-4
- LAST UPDATED :
- 199110
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C14-H21-N-O4
- MOLECULAR WEIGHT :
- 267.36
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PBPSDY Pharmacological and Biochemical Properties of Drug Substances. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.1- 1977- Volume(issue)/page/year: 2,186,1979
美托洛尔酸安全信息
[ 符号 ]:
GHS07
[ 信号词 ]:
Warning
[ 危害声明 ]:
H302
[ 危险品运输编码 ]:
NONH for all modes of transport
[ RTECS号 ]:
CY1634360
美托洛尔酸文献
Int. J. Environ. Res. Public Health 11(10) , 10390-405, (2014)
Attenuation of micro-contaminants is a very complex field in environmental science and evidence suggests that biodegradation rates of micro-contaminants in the aqueous environment depend on the water ...
Pregnancy-induced increase in metoprolol metabolism.Clin. Pharmacol. Ther. 37(6) , 688-92, (1985)
Five women who developed hypertension during pregnancy received metoprolol, 10 mg iv; 3 days later they received metoprolol, 100 mg by mouth. Blood and urine samples were collected after each dose. Th...
Determination of two metoprolol metabolites in human urine by high-performance liquid chromatography.J. Chromatogr. A. 309(1) , 198-202, (1984)
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推荐生产厂家/供应商:
公司名:上海化源世纪贸易有限公司
区域:上海市普陀区
价格:
联系人:徐经理
产品详情:美托洛尔酸
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥1999.9/10mg
¥需询单/1g
¥需询单/1g
¥需询单/1g
联系人:阿拉丁
产品详情:美托洛尔酸
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相关化合物
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