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4-溴-2-氟苯甲醛

4-溴-2-氟苯甲醛用途

用于合成医药、农药中间体

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4-溴-2-氟苯甲醛名称

[ CAS 号 ]:
57848-46-1

[ 中文名 ]:
4-溴-2-氟苯甲醛

[ 英文名 ]:
4-Bromo-2-fluorobenzaldehyde

[中文别名 ]:

[英文别名 ]:

4-bromo-6-fluorobenzaldehyde
Benzaldehyde, 4-bromo-2-fluoro-
VHR BF DE
MFCD00143261
4-Brom-2-fluorbenzolcarbaldehyd
4-Bromo-2-fluorobenzaldehyde
2-Fluoro-4-bromobenzaldehyde
4-bromo2-fluorobenzaldehyde
benzaldehyde,4-bromo-2-fluoro

4-溴-2-氟苯甲醛物理化学性质

[ 密度 ]:
1.7±0.1 g/cm3

[ 沸点 ]:
241.4±25.0 °C at 760 mmHg

[ 熔点 ]:
59-64 °C

[ 分子式 ]:
C₇H₄BrFO

[ 分子量 ]:
203.008

[ 闪点 ]:
99.8±23.2 °C

[ 精确质量 ]:
201.942947

[ PSA ]:
17.07000

[ LogP ]:
2.71

[ 外观性状 ]:
淡黄色至米色结晶固体,晶体

[ 蒸汽压 ]:
0.0±0.5 mmHg at 25°C

[ 折射率 ]:
1.585

[ 储存条件 ]:
Room temperature.

[ 水溶解性 ]:
INSOLUBLE

4-溴-2-氟苯甲醛MSDS

4-溴-2-氟苯甲醛安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S37/39-S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2913000090

4-溴-2-氟苯甲醛合成路线

4-溴-2-氟苯甲醛上下游产品

4-溴-2-氟苯甲醛上游产品

4-溴-2-氟苯甲醛下游产品

4-溴-2-氟苯甲醛海关

[ 海关编码 ]: 2913000090

[ 中文概述 ]:
2913000090 品目2912所列产品的其他衍生物〔指卤化,磺化,硝化或亚硝化的衍生物〕. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%

4-溴-2-氟苯甲醛文献

Synthesis and biological evaluation of 2'-oxo-2,3-dihydro-3'H- spiro[chromene-4,5'-[1,3]oxazolidin]-3'yl]acetic acid derivatives as aldose reductase inhibitors.

Arch. Pharm. (Weinheim) 344(6) , 372-85, (2011)

Aldose reductase (ARL2) is the first enzyme in the polyol pathway which catalyzes the NADPH-dependent reduction of glucose to sorbitol. Its involvement on diabetic complications makes this enzyme a ch...

Synthesis of tri-substituted biaryl based trianglimines: formation of C3-symmetrical and non-symmetrical regioisomers.

Org. Biomol. Chem. 9(9) , 3258-71, (2011)

2-Functionalised aromatic monoaldehydes were synthesised in good to excellent yields by reacting 4-bromo-2-fluorobenzaldehyde with different secondary amines and phenol. The Suzuki-coupling reaction o...

Benzylamine histamine H(3) antagonists and serotonin reuptake inhibitors.

Bioorg. Med. Chem. Lett. 17(17) , 4799-803, (2007)

The design, synthesis, and in vitro activity of a series of novel 5-ethynyl-2-aryloxybenzylamine-based histamine H(3) ligands that are also serotonin reuptake transporters is described.

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