DICHLORO(4-METHYL-o-PHENYLENEDI-AMMINE)PLATINUM(II)
名称
[ CAS 号 ]:
57948-13-7
[ 英文名 ]:
DICHLORO(4-METHYL-o-PHENYLENEDI-AMMINE)PLATINUM(II)
[英文别名 ]:
- dichloro-1,3 methoxycarbonylhydrazono-2 propane
物理化学性质
[ 沸点 ]:
262.3ºC at 760 mmHg
[ 分子式 ]:
C7H8Cl2N2Pt
[ 分子量 ]:
386.13600
[ 闪点 ]:
132.1ºC
[ 精确质量 ]:
384.97100
[ PSA ]:
24.06000
[ LogP ]:
3.39990
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TP2497220
- CHEMICAL NAME :
- Platinum (II), dichloro(4-methyl-o-phenylenediammine)-
- CAS REGISTRY NUMBER :
- 57948-13-7
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C7-H10-Cl2-N2-Pt
- MOLECULAR WEIGHT :
- 388.18
- WISWESSER LINE NOTATION :
- ZR BZ D1 &G-PT-G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 23 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 2500 nmol/L
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,459,1980
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