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吡啶甲醇

吡啶甲醇用途

2-吡啶甲醇是一种吡啶醇,具有降血糖活性[1]。

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吡啶甲醇名称

[ CAS 号 ]:
586-98-1

[ 中文名 ]:
2-吡啶甲醇

[ 英文名 ]:
piconol

[中文别名 ]:

[英文别名 ]:

2-PYRIDYLCARBINOL
Pyridine-2-carbinol
2-Pyridinylmethanol
(pyridin-2-yl)methanol
a-Picolyl Alcohol
2-HMP
piconol
EINECS 209-592-7
2-PICOLYL ALCOHOL
2-hydroxymethylpyridine

吡啶甲醇生物活性

[ 描述 ]:

2-吡啶甲醇是一种吡啶醇,具有降血糖活性[1]。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 代谢疾病

[参考文献]

[1]. Kim DS, et al. Hydroesterification of alkenes with sodium formate and alcohols promoted by cooperative catalysis of Ru3(CO)12 and 2-pyridinemethanol. J Org Chem. 2014 Dec 19;79(24):12191-6.

吡啶甲醇物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
222.6±0.0 °C at 760 mmHg

[ 熔点 ]:
5 °C

[ 分子式 ]:
C₆H₇NO

[ 分子量 ]:
109.126

[ 闪点 ]:
81.7±20.4 °C

[ 精确质量 ]:
109.052765

[ PSA ]:
33.12000

[ LogP ]:
-0.46

[ 外观性状 ]:
透明黄色液体

[ 蒸汽压 ]:
0.1±0.4 mmHg at 25°C

[ 折射率 ]:
1.551

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
miscible

吡啶甲醇MSDS

吡啶甲醇毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UT4689000

CHEMICAL NAME :: 2-Pyridinemethanol

CAS REGISTRY NUMBER :: 586-98-1

BEILSTEIN REFERENCE NO. :: 0107849

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H7-N-O

MOLECULAR WEIGHT :: 109.14

WISWESSER LINE NOTATION :: T6NJ B1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 11,242,1956

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 12,355,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - wild bird species

DOSE/DURATION :: 750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 12,355,1983

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吡啶甲醇安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R22;R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
UT4689000

[ 海关编码 ]:
29333999

吡啶甲醇合成路线

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吡啶甲醇下游产品

吡啶甲醇海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

吡啶甲醇文献

Self-assembled hybrid metal oxide base catalysts prepared by simply mixing with organic modifiers.

Nat. Commun. 6 , 8580, (2015)

Multidentate materials formed by simply mixing heterogeneous and homogeneous components are promising for construction of versatile active sites on the surface of heterogeneous compounds, however, to ...

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