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4-甲酰苯甲酸N-琥珀酰亚胺酯

4-甲酰苯甲酸N-琥珀酰亚胺酯用途

Ald-Ph-NHS ester 是一种不可降解的 linker,可用于合成抗体偶联药物 (ADC)。

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4-甲酰苯甲酸N-琥珀酰亚胺酯名称

[ CAS 号 ]:
60444-78-2

[ 中文名 ]:
对甲酰基苯甲酸-N-羟基琥珀酰亚胺酯

[ 英文名 ]:
Ald-Ph-NHS ester

[中文别名 ]:

[英文别名 ]:

(2,5-dioxopyrrolidin-1-yl) 4-formylbenzoate

4-甲酰苯甲酸N-琥珀酰亚胺酯生物活性

[ 描述 ]:

Ald-Ph-NHS ester 是一种不可降解的 linker,可用于合成抗体偶联药物 (ADC)。

[ 相关类别 ]:

研究领域 >> 癌症

[ 靶点 ]

Noncleavable

4-甲酰苯甲酸N-琥珀酰亚胺酯物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
425.4±47.0 °C at 760 mmHg

[ 熔点 ]:
163ºC

[ 分子式 ]:
C₁₂H₉NO₅

[ 分子量 ]:
247.204

[ 闪点 ]:
211.1±29.3 °C

[ 精确质量 ]:
247.048065

[ PSA ]:
80.75000

[ LogP ]:
-0.20

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.606

[ 储存条件 ]:
-20°C

4-甲酰苯甲酸N-琥珀酰亚胺酯MSDS

4-甲酰苯甲酸N-琥珀酰亚胺酯安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2925190090

4-甲酰苯甲酸N-琥珀酰亚胺酯合成路线

4-甲酰苯甲酸N-琥珀酰亚胺酯上下游产品

4-甲酰苯甲酸N-琥珀酰亚胺酯上游产品

4-甲酰苯甲酸N-琥珀酰亚胺酯下游产品

4-甲酰苯甲酸N-琥珀酰亚胺酯海关

[ 海关编码 ]: 2925190090

[ 中文概述 ]:
2925190090 其他酰亚胺及其衍生物盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

4-甲酰苯甲酸N-琥珀酰亚胺酯文献

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Metastatic prostate cancer causes significant morbidity and mortality and there is a critical unmet need for effective treatments. We have developed a theranostic nanoplex platform for combined imagin...

A strategy for the systematic development of a liquid chromatographic mass spectrometric screening method for polymer electrolyte membrane degradation products using isocratic and gradient phase optimized liquid chromatography.

J. Chromatogr. A. 1216 , 8910-8917, (2009)

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Synthesis of pH-sensitive amphotericin B-poly(ethylene glycol) conjugates and study of their controlled release in vitro.

Bioorg. Med. Chem. 15 , 4069-4076, (2007)

New intravenous conjugates of amphotericin B (AMB) with poly(ethylene glycols) (PEG) (M=5000, 10,000, 20,000) have been synthesized and characterised. The intermediate PEGs possess a 1,4-disubstituted...

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