二氧化硅

二氧化硅用途

1.在晶体管和集成电路中作杂质扩散的掩蔽膜和保护层。作为填料用于环氧铸塑、光导纤维、涂料等领域。还可用于制造玻璃、发射光谱分析试剂、固体电路生产中扩锑时控制锑浓度等方面。

2.在饲料添加剂中主要作为抗结剂使用，以防止饲料结块而影响吸收。二氧化硅具有很好的分散性，有较大的比表面积和超强的吸附性能，可作为各种饲料添加剂的载体和分散剂，是各种水、油性物质变成固态物质的良好载体。广泛用作涂料工业的增稠剂、消光剂、塑料薄膜的开口剂，也是晒图纸预涂液的主要成分。

活性白炭黑：

本品外观呈球形颗粒，易混炼不飞扬，用作橡胶的补强剂。其硫化胶制品的抗张强度、硬度、曲挠、撕裂、磨耗、热老化等方面表现出优良的特性，远超过普通沉淀白炭黑。在透明和彩色胶制品中是不可缺少的材料。主要用于彩电电缆、电线套管、跑道胶、橡胶水管、橡胶透明鞋底、彩色鞋底、微孔鞋底及其他橡胶制品。还用于乳胶、塑料薄膜、皮革、涂料、黏合剂、造纸、农药、化妆品、消光剂、增稠剂、触变剂等。

用作密封胶的填充剂，可以代替陶土、轻质碳酸钙和沉淀白炭黑。

点击显示

二氧化硅名称

[ CAS 号 ]:
60676-86-0

[ 中文名 ]:
纳米二氧化硅

[ 英文名 ]:
Silica glass

[中文别名 ]:

[英文别名 ]:

Dioxosilane
Silica glass
Cristobalite
MFCD00011232
EINECS 262-373-8
Silane, dioxo-

二氧化硅物理化学性质

[ 密度 ]:
2.6

[ 沸点 ]:
2230ºC

[ 熔点 ]:
1610ºC

[ 分子式 ]:
O₂Si

[ 分子量 ]:
60.084

[ 精确质量 ]:
59.966755

[ PSA ]:
34.14000

[ 外观性状 ]:
无色,无气味的固体

[ 折射率 ]:
n20/D 1.544(lit.)

[ 储存条件 ]:
室温

二氧化硅MSDS

详细MSDS(安全技术说明书)

二氧化硅毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VV7328000

CHEMICAL NAME :: Silica, crystalline - fused

CAS REGISTRY NUMBER :: 60676-86-0

LAST UPDATED :: 199712

DATA ITEMS CITED :: 28

MOLECULAR FORMULA :: O2-Si

MOLECULAR WEIGHT :: 60.09

WISWESSER LINE NOTATION :: SI O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - fibrosis (interstitial) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 9,389,1954

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intratracheal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 120 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - changes in pulmonary vascular resistance Lungs, Thorax, or Respiration - acute pulmonary edema

REFERENCE :: AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 9,389,1954

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Gastrointestinal - other changes

REFERENCE :: BJEPA5 British Journal of Experimental Pathology. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.1- 1920- Volume(issue)/page/year: 3,75,1922

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 26,774,1941

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 35 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Cardiac - other changes Lungs, Thorax, or Respiration - other changes

REFERENCE :: BJEPA5 British Journal of Experimental Pathology. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.1- 1920- Volume(issue)/page/year: 3,75,1922 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 197 mg/m3/6H/26W-I

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - changes in lung weight

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 22(6),28,1978 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Implant

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 400 mg/kg

REFERENCE :: NATWAY Naturwissenschaften. (Springer-Verlag, Heidelberger Platz 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1913- Volume(issue)/page/year: 41,534,1954 *** REVIEWS *** ACGIH TLV-TWA 0.1 mg/m3, respirable dust DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 42,39,1987 IARC Cancer Review:Human Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 42,39,1987 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 68,41,1997 IARC Cancer Review:Group 2A IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,341,1987 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-respirable dust in air:TWA 10 mg/m3/% resp. SiO2+2 DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8. Volume(issue)/page/year: 3,33,1973 MSHA STANDARD-total dust in air:TWA 30 mg/m3/% SiO2+3 DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8. Volume(issue)/page/year: 3,33,1973 OSHA PEL (Gen Indu):8H TWA 10 mg/m3/(% resp SiO2+2) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 10 mg/m3/(% resp SiO2+2) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Fed Cont):8H TWA 10 mg/m3/(% resp SiO2+2), resp. dust CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FINLAND:TWA 5 mg/m3 JAN 1993 OEL-GERMANY:TWA 0.3 mg/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.1 mg/m3 (resp. dust) JAN 1993 OEL-UNITED KINGDOM:TWA 0.3 mg/m3 (total dust) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO SILICA, fused-air:10H CA TWA 0.05 mg/m3 REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4331 No. of Facilities: 480 (estimated) No. of Industries: 8 No. of Occupations: 14 No. of Employees: 6475 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M4331 No. of Facilities: 4174 (estimated) No. of Industries: 68 No. of Occupations: 60 No. of Employees: 52205 (estimated) No. of Female Employees: 7320 (estimated)

点击显示

二氧化硅安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Warning

[ 危害声明 ]:
H319-H335-H373

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 靶器官 ]:
Lungs

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
T: Toxic;Xn: Harmful;

[ 风险声明 (欧洲) ]:
R48/20

[ 安全声明 (欧洲) ]:
22-24/25-45-26-53

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
VV7311000

[ 海关编码 ]:
7020009901

二氧化硅制备

1、沉淀法又称液相法或凝胶法
（1）原料配置将模数为3.1～3.4的工业级水玻璃用泵送至陶瓷缸或陶瓷容器中，在搅拌下加入自来水，稀释至二氧化硅含量在15%左右，停止搅拌，自然沉降48h后即可进行后续工艺处理。
（2）中和成胶在搪瓷成胶釜中加入自来水52.16份，再将上述配置的水玻璃57.94份加入釜中，搅拌均匀，配成二氧化硅含量为9%的水玻璃溶液，釜内温度升至30℃。一边搅拌，一边滴加硫酸（40%浓度），滴加速度为0.21～0.23份/min。共加酸5.58份，加酸时间约25min，此时釜内出现白色凝胶，停止加酸，继续搅拌5min，测定pH值，如pH值达10.5，准备酸化。
（3）酸化和老化加热升温使釜内温度达80℃时，在搅拌下滴加硫酸，加酸速度0.172～0.173份/min，硫酸浓度为40%。酸化终点为pH值等于3。然后继续搅拌，并将釜温升至100℃，保持1h进行老化。
（4）洗涤过滤将上述制备的水凝胶用泵送到板框压滤机，泵出口压力不超过0.3MPa，一般为0.22MPa，压滤至无滤液流出。然后将清水从洗涤口以0.3MPa的压力压入，进行洗涤。再用0.2MPa左右压力的压缩空气正吹15min，使滤饼易于卸下。滤饼卸出后放入打浆罐，加水并开启搅拌，将滤饼搅拌成均匀的水凝胶悬浮液，然后用泵送到压滤机再次过滤。将上述操作重复两次，再用去离子水洗两次，分析滤饼的钠离子含量是否小于0.2%。若未小于0.2%，需再用去离子水洗涤、压滤。达到要求后，将滤饼卸下，其固含量约为18%～20%。
（5）喷雾干燥将滤饼配成均匀的悬浮液，由加料泵送到离心雾化干燥器的进口，调节热空气进口温度为300℃，出口温度为130℃，风量100kg/h，可得球形较好的细粒度二氧化硅。粒径分布为10～20μm的粒子占12.6%，粒径0～10μm的占70%，小于2μm的粒子占17.4%。

2、气化法又称燃烧法将四氯化硅在高温下气化，四氯化硅气体在氢气和空气的均匀混合物中于1000～1200℃下，进行气相水解反应，生成极微细的白炭黑。然后通过旋风分离器，将白炭黑与气体分离，再在白炭黑中吹入氨或干空气进行脱酸。即可包装。

活性白炭黑：

（1）溶胶的制备将工业盐酸配制成10～12°Bé的盐酸溶液；将工业硅酸钠沉淀去渣后，配制成20°Bé的溶液。在溶胶配制槽中先加入上述配制的10～12°Bé盐酸为底液。在搅拌下加入上述配好的20°Bé的硅酸钠溶液，控制好投料速度，待溶液中二氧化硅含量达到6.5%～8.5%时。便得溶胶。
（2）中和反应反应器可采用搪瓷搅拌或不锈钢搅拌釜。将工业硅酸钠配制成10°Bé的水溶液投入反应釜，搅拌下微微加热并缓缓加入上述配制的胶液，同时加入12°Bé氯化钠溶液。在加胶的过程中，控制反应温度70℃左右。当反应过程中析出沉淀和pH值7.8～8.2时，要注意随时用碱性调节液调节反应物料的pH值，保持pH值为7.8～8.2，直到反应结束。然后加入浓盐酸，使反应系统微酸性，保温下陈化半小时，放料。

（3）漂洗和干燥将反应产物中沉淀物与溶液分离，沉淀物用自来水漂洗、过滤，直到氯化钠含量小于1.5%为止，然后用去离子水再洗涤、过滤1～2次。漂洗好的沉淀物在150℃下静态干燥6h，即可除去大部分水，最后控制其含水量小于6%。若产品量较大，需采用其他干燥方式，如喷雾干燥、沸腾干燥等。

点击显示

二氧化硅海关

[ 海关编码 ]: 7020009901

二氧化硅文献

Functional characterisation and permeation studies of lyophilised thiolated chitosan xerogels for buccal delivery of insulin.

Protein Pept. Lett. 21(11) , 1163-75, (2014)

Stable and mucoadhesive, lyophilised, thiolated chitosan xerogels, loaded with insulin for buccal mucosa deliv- ery, in place of the currently used parenteral route have been developed. The xerogels w...

Vacuolar-ATPase isoform a2 regulates macrophages and cytokine profile necessary for normal spermatogenesis in testis.

J. Leukoc. Biol. 96(2) , 337-47, (2014)

a2V is required for maturation of sperm. The decreased expression of a2V at the feto-maternal interphase causes poor pregnancy outcome. The present study examined the role of a2V in spermatogenesis an...

Hemocompatibility evaluation of small elastomeric hollow fiber membranes as vascular substitutes.

J. Biomater. Appl. 29(4) , 557-65, (2014)

One of the main challenges for clinical implementation of small diameter vascular grafts (SDVGs) is their limited hemocompatibility. Important design specifications for such grafts include features th...

更多文献

二氧化硅

二氧化硅用途

二氧化硅名称

二氧化硅物理化学性质

二氧化硅MSDS

详细MSDS(安全技术说明书)

二氧化硅毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

二氧化硅安全信息

二氧化硅制备

二氧化硅海关

二氧化硅文献

相关化工产品/化学物质：

推荐生产厂家/供应商：

相关化合物