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8-甲基喹啉

8-甲基喹啉名称

[ CAS 号 ]:
611-32-5

[ 中文名 ]:
8-甲基喹啉

[ 英文名 ]:
8-Methylquinoline

[中文别名 ]:

[英文别名 ]:

Quinoline,8-methyl
8-methyl quinoline
Quinoline, 8-methyl-
8-Methyl-chinolin
O-Toluquinoline
MFCD00006810
8-Methylquinoline
EINECS 210-264-0
Fasudil Impurity 11

8-甲基喹啉物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
247.5±0.0 °C at 760 mmHg

[ 熔点 ]:
-80 °C

[ 分子式 ]:
C₁₀H₉N

[ 分子量 ]:
143.185

[ 闪点 ]:
105.0±0.0 °C

[ 精确质量 ]:
143.073502

[ PSA ]:
12.89000

[ LogP ]:
2.54

[ 外观性状 ]:
淡棕色油性液体

[ 蒸汽压 ]:
0.0±0.4 mmHg at 25°C

[ 折射率 ]:
1.625

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

[ 水溶解性 ]:
0.1-0.5 g/100 mL at 17 ºC

8-甲基喹啉MSDS

8-甲基喹啉毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VC0562000

CHEMICAL NAME :: Quinoline, 8-methyl-

CAS REGISTRY NUMBER :: 611-32-5

BEILSTEIN REFERENCE NO. :: 0111340

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H9-N

MOLECULAR WEIGHT :: 143.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Unscheduled DNA synthesis

TEST SYSTEM :: Rodent - rat Liver

DOSE/DURATION :: 1 mmol/L

REFERENCE :: CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 12,217,1991

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8-甲基喹啉安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R22;R36/37/38;R68

[ 安全声明 (欧洲) ]:
S26-S36-S45-S36/37/39

[ 危险品运输编码 ]:
2810.0

[ WGK德国 ]:
3

[ RTECS号 ]:
VC0562000

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2933499090

8-甲基喹啉合成路线

8-甲基喹啉上下游产品

8-甲基喹啉上游产品

8-甲基喹啉下游产品

8-甲基喹啉海关

[ 海关编码 ]: 2933499090

[ 中文概述 ]:
2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

8-甲基喹啉文献

A P450 BM-3 mutant hydroxylates alkanes, cycloalkanes, arenes and heteroarenes.

J. Biotechnol. 88(2) , 167-71, (2001)

P450 monooxygenases from microorganisms, similar to those of eukaryotic mitochondria, display a rather narrow substrate specificity. For native P450 BM-3, no other substrates than fatty acids or an in...

The hepatic metabolism of two methylquinolines.

Carcinogenesis 14(5) , 1041-7, (1993)

The hepatic microsomal metabolism of the carcinogenic 8-methylquinoline (8MQ) and its noncarcinogenic isomer, 6-methylquinoline (6MQ), were compared for preparations from control rats and rats pretrea...

Carcinogenicity of quinoline, 4- and 8-methylquinoline and benzoquinolines in newborn mice and rats.

Food Chem. Toxicol. 26(7) , 625-9, (1988)

The relative tumorigenic activity of quinoline, 4-methylquinoline, 8-methylquinoline, and all three isomeric benzoquinolines was evaluated in newborn CD-1 mice and Sprague-Dawley rats. In the newborn-...

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