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α-甲基-D-甘露糖苷

α-甲基-D-甘露糖苷用途

Methyl α-D-mannopyranoside 在抗结核吸入疗法中靶向巨噬细胞。

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α-甲基-D-甘露糖苷名称

[ CAS 号 ]:
617-04-9

[ 中文名 ]:
α-甲基-D-甘露糖苷

[ 英文名 ]:
Methyl α-D-mannopyranoside

[中文别名 ]:

[英文别名 ]:

MFCD00063262
EINECS 210-502-3
Methyl α-D-mannopyranoside
α-D-Mannopyranoside, methyl
Methyl .α.-D-mannopyranoside
Methyl a-D-Mannopyranoside

α-甲基-D-甘露糖苷生物活性

[ 描述 ]:

Methyl α-D-mannopyranoside 在抗结核吸入疗法中靶向巨噬细胞。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

[参考文献]

[1]. Maretti E, et, al. Surface engineering of Solid Lipid Nanoparticle assemblies by methyl α-d-mannopyranoside for the active targeting to macrophages in anti-tuberculosis inhalation therapy. Int J Pharm. 2017 Aug 7; 528(1-2):440-451.

α-甲基-D-甘露糖苷物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
389.1±42.0 °C at 760 mmHg

[ 熔点 ]:
193-196ºC

[ 分子式 ]:
C₇H₁₄O₆

[ 分子量 ]:
194.182

[ 闪点 ]:
189.1±27.9 °C

[ 精确质量 ]:
194.079041

[ PSA ]:
99.38000

[ LogP ]:
-2.69

[ 外观性状 ]:
白色粉末

[ 蒸汽压 ]:
0.0±2.0 mmHg at 25°C

[ 折射率 ]:
1.548

[ 储存条件 ]:
Refrigerator

[ 水溶解性 ]:
H2O: 0.1 g/mL, clear

α-甲基-D-甘露糖苷MSDS

详细MSDS(安全技术说明书)

α-甲基-D-甘露糖苷安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi,F

[ 风险声明 (欧洲) ]:
10

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

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α-甲基-D-甘露糖苷文献

Synthesis of glycopeptide dendrimers, dimerization and affinity for Concanavalin A.

Bioorg. Med. Chem. 19 , 2879-87, (2011)

We described herein the synthesis of second generation glycopeptide dendrimers G2a-g presenting variable amino acids placed internally into the multivalent scaffold. The effect of such structural modu...

Redox-responsive and calcium-dependent switching of glycosyldisulfide interactions with Concanavalin A.

Bioorg. Med. Chem. Lett. 15 , 2707-10, (2005)

Glycosyldisulfides can interact efficiently with carbohydrate-binding entities. This has been shown for a range of thiosaccharide dimers when tested for their effects against the lectin Concanavalin A...

BK Virus replication in vitro: limited effect of drugs interfering with viral uptake and intracellular transport.

Antimicrob. Agents Chemother. 51 , 4492-4, (2007)

BK virus is an important pathogen in kidney transplant recipients. In vitro studies demonstrated slight antiviral activity for chloroquine and nystatin. A sialic acid derivative, BTB11968, was identif...

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