6-氯苯并[d]异噁唑-3-醇

6-氯苯并[d]异噁唑-3-醇用途

CBIO is a potent, cell-permeable, D-amino acid oxidase (DAO) reversible inhibitor. In rat models, CBIO prevents formalin-induced tonic pain but not acute nociception.

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6-氯苯并[d]异噁唑-3-醇名称

[ CAS 号 ]:
61977-29-5

[ 中文名 ]:
6-氯苯并[D]异恶唑-3-醇

[ 英文名 ]:
6-Chlorobenzo[D]Isoxazol-3-Ol

[中文别名 ]:

[英文别名 ]:

6-Chloro-1,2-benzoxazol-3(2H)-one
1,2-Benzisoxazol-3(2H)-one, 6-chloro-
6-chloro-1,2-benzoxazol-3-one
6-Chlorobenzo[D]Isoxazol-3-Ol

6-氯苯并[d]异噁唑-3-醇物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
336.7±22.0 °C at 760 mmHg

[ 熔点 ]:
218-220ºC

[ 分子式 ]:
C₇H₄ClNO₂

[ 分子量 ]:
169.565

[ 闪点 ]:
157.4±22.3 °C

[ 精确质量 ]:
168.993057

[ PSA ]:
46.26000

[ LogP ]:
1.49

[ 外观性状 ]:
灰色固体

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.674

[ 储存条件 ]:
2-8°C，密封，干燥

6-氯苯并[d]异噁唑-3-醇MSDS

6-氯苯并[d]异噁唑-3-醇安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26-36/37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2934999090

6-氯苯并[d]异噁唑-3-醇合成路线

6-氯苯并[d]异噁唑-3-醇上下游产品

6-氯苯并[d]异噁唑-3-醇上游产品

6-氯苯并[d]异噁唑-3-醇下游产品

6-氯苯并[d]异噁唑-3-醇海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

6-氯苯并[d]异噁唑-3-醇文献

Salmonella evades D-amino acid oxidase to promote infection in neutrophils.

MBio 5(6) , e01886, (2014)

Neutrophils engulf and kill bacteria using oxidative and nonoxidative mechanisms. Despite robust antimicrobial activity, neutrophils are impaired in directing Salmonella clearance and harbor viable in...

Contributions of spinal D-amino acid oxidase to chronic morphine-induced hyperalgesia.

J. Pharm. Biomed. Anal. 116 , 131-8, (2015)

Spinal D-amino acid oxidase (DAAO) is an FAD-dependent peroxisomal flavoenzyme which mediates the conversion of neutral and polar D-amino acids (including D-serine) to the corresponding α-keto acids, ...

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