SEPTACIDIN

SEPTACIDIN用途

Septacidin 是一种腺嘌呤核苷抗生素,具有抗真菌和抗肿瘤活性。

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SEPTACIDIN名称

[ CAS 号 ]:
62362-59-8

[ 英文名 ]:
SEPTACIDIN

[英文别名 ]:

Septacidin

SEPTACIDIN生物活性

[ 描述 ]:

Septacidin 是一种腺嘌呤核苷抗生素,具有抗真菌和抗肿瘤活性。

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> 真菌

[参考文献]

[1]. Meng Chen, et al. Discovery of novel septacidin congeners from a high yield heterologous expression strain Streptomyces albus 1597. J Antibiot (Tokyo). 2022 Mar;75(3):172-175.

SEPTACIDIN物理化学性质

[ 密度 ]:
1.28g/cm3

[ 沸点 ]:
979.6ºC at 760 mmHg

[ 分子式 ]:
C₃₀H₅₁N₇O₇

[ 分子量 ]:
621.76900

[ 闪点 ]:
546.2ºC

[ 精确质量 ]:
621.38500

[ PSA ]:
214.84000

[ LogP ]:
2.35770

[ 折射率 ]:
1.593

SEPTACIDIN毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MJ9850000

CHEMICAL NAME :: L-glycero-beta-L-gluco-Heptopyranosylamine, 4-deoxy-4-((((14-methyl-1-oxopentadecyl)amino) acetyl)amino)-N-1H-purin-6-yl-

CAS REGISTRY NUMBER :: 62362-59-8

LAST UPDATED :: 199504

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C30-H51-N7-O7

MOLECULAR WEIGHT :: 621.88

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 5,303,1981

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AACHAX Antimicrobial Agents and Chemotherapy (1961-70). (Ann Arbor, MI) 1961-70. For publisher information, see AMACCQ. Volume(issue)/page/year: -.83,1963