D-缬氨酸

D-Valine 是 L-Valine (HY-N0717) 的对映体。L-Valine 是二十种蛋白氨基酸中的其中一种。L-Valine 是一种必需氨基酸。

[ 描述 ]:

[ 相关类别 ]:

[ 靶点 ]

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
213.6±23.0 °C at 760 mmHg

[ 熔点 ]:
>295 °C (subl.)(lit.)

[ 分子式 ]:
C₅H₁₁NO₂

[ 分子量 ]:
117.146

[ 闪点 ]:
83.0±22.6 °C

[ 精确质量 ]:
117.078979

[ PSA ]:
63.32000

[ LogP ]:
0.20

[ 外观性状 ]:
白色晶体

[ 蒸汽压 ]:
0.1±0.9 mmHg at 25°C

[ 折射率 ]:
1.461

[ 储存条件 ]:
室温

[ 水溶解性 ]:
56 g/L (20 ºC)

详细MSDS(安全技术说明书)

CHEMICAL IDENTIFICATION

RTECS NUMBER :

YV9360000

CHEMICAL NAME :

Valine, D-

CAS REGISTRY NUMBER :

640-68-6

LAST UPDATED :

199706

DATA ITEMS CITED :

3

MOLECULAR FORMULA :

C5-H11-N-O2

MOLECULAR WEIGHT :

117.17

WISWESSER LINE NOTATION :

QVYZY1&1 -D

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

6093 mg/kg

TOXIC EFFECTS :

Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :

ABBIA4 Archives of Biochemistry and Biophysics. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.31- 1951- Volume(issue)/page/year: 64,319,1956 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9991 No. of Facilities: 35 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 115 (estimated) No. of Female Employees: 64 (estimated)

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
YV9360000

[ 海关编码 ]:
29224995

详细合成路线

D-缬氨酸上游产品

D-缬氨酸下游产品

【方法一】
其制备方法是用2-异丙基乙酰乙酸乙酯与苯重氮盐反应生成相应的肼化合物，再在锌-乙醇溶液中还原成缬氨酸，再进行化学或生物拆分。
【方法二】
以乙酰-DL-缬氨酸为原料，经酰化酶拆分、盐酸酸化析出D-缬氨酸晶体，再经重结晶精制得产品。

[ 海关编码 ]: 2922499990

[ 中文概述 ]:
2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Salmonella evades D-amino acid oxidase to promote infection in neutrophils.

MBio 5(6) , e01886, (2014)

Neutrophils engulf and kill bacteria using oxidative and nonoxidative mechanisms. Despite robust antimicrobial activity, neutrophils are impaired in directing Salmonella clearance and harbor viable in...

Vitamin D reverses aPL-induced inflammation and LMWH-induced sFlt-1 release by human trophoblast.

Am. J. Reprod. Immunol. 73(3) , 242-50, (2015)

Women with antiphospholipid syndrome (APS) are at increased risk of recurrent pregnancy loss (RPL) and preeclampsia. Antiphospholipid antibodies (aPL) directly alter trophoblast function. Treatment wi...

Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).

Bioorg. Med. Chem. 19 , 6409-18, (2011)

The proton-coupled amino acid transporter hPAT1 has recently gained much interest due to its ability to transport small drugs thereby allowing their oral administration. A three-dimensional quantitati...

更多文献

公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐乾明

产品详情：D-缬氨酸

---

公司名：吉尔生化（上海）有限公司

区域：上海市闵行区

价格：
$需询单/1kg

联系人：杨经理

产品详情：H-D-Val-OH

---

公司名：上海吉至生化科技有限公司

区域：上海市奉贤区

价格：
￥268.0/100g ￥128.0/25g ￥828.0/500g ￥1408.0/1kg

联系人：刘佳

产品详情：D-缬氨酸

---

公司名：南京肽业生物科技有限公司

区域：南京市六合区

价格：
￥需询单/10g ￥需询单/100g ￥需询单/1kg ￥需询单/10kg

联系人：滕经理

产品详情：H-D-Val-OH

---

公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥29.9/1g ￥61.9/25g ￥517.9/500g ￥41.9/5g

联系人：阿拉丁

产品详情：D-缬氨酸

---

查看所有供应商请点击：

D-缬氨酸供应商