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虎杖甙

虎杖甙用途

(E/Z)-Polydatin (E/Z)-Piceid) 是一种单晶化合物,最初从虎杖的根和根茎中分离得到。(E/Z)-Polydatin 具有抗血小板聚集、抗低密度脂蛋白 (LDL) 氧化作用、心脏保护作用、抗炎和免疫调节功能。

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虎杖甙名称

[ CAS 号 ]:
65914-17-2

[ 中文名 ]:
虎杖甙

[ 英文名 ]:
(E/Z)-Polydatin

[中文别名 ]:

白藜芦醇甙

[英文别名 ]:

3,4,5-Tsg
trans-polydatin
MFCD00210592
(E)-Polydatin
Trans-Piceid
Giant knotweed Extract
Piceid
Reservatrol-3-β-mono-D-glucoside
Polydatin

虎杖甙生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

[参考文献]

[1]. Du QH, et al. Polydatin: a review of pharmacology and pharmacokinetics. Pharm Biol. 2013 Nov;51(11):1347-54.

虎杖甙物理化学性质

[ 密度 ]:
1.521 g/cm3

[ 沸点 ]:
707.7ºC at 760 mmHg

[ 熔点 ]:
223-226 °C(lit.)

[ 分子式 ]:
C₂₀H₂₂O₈

[ 分子量 ]:
407.39100

[ 闪点 ]:
381.8ºC

[ 精确质量 ]:
407.13400

[ PSA ]:
160.07000

[ LogP ]:
0.49640

[ 储存条件 ]:
室温

虎杖甙MSDS

详细MSDS(安全技术说明书)

虎杖甙安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

虎杖甙文献

Protective effect of polydatin against burn-induced lung injury in rats.

Respir. Care 59(9) , 1412-21, (2014)

Polydatin (PD) has anti-inflammatory and anti-apoptotic effects in ischemic-reperfusion injury. Moreover, inflammatory responses and apoptosis play a role in the development of burn-induced lung injur...

Nephroprotective Effects of Polydatin against Ischemia/Reperfusion Injury: A Role for the PI3K/Akt Signal Pathway.

Oxid. Med. Cell. Longev. 2015 , 362158, (2015)

Oxidative stress and inflammation are involved in the pathogenesis in renal ischemia/reperfusion (I/R) injury. It has been demonstrated that polydatin processed the antioxidative, anti-inflammatory, a...

Pre-column incubation followed by fast liquid chromatography analysis for rapid screening of natural methylglyoxal scavengers directly from herbal medicines: case study of Polygonum cuspidatum.

J. Chromatogr. A. 1286 , 102-10, (2013)

Methylglyoxal (MGO), a very reactive metabolite of glucose, plays a pivotal role in the pathogenesis of several chronic diseases associated with diabetes, and it has been validated as an attractive ta...

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虎杖甙