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4-(1-芘基)-1-丁醇

4-(1-芘基)-1-丁醇用途

1-芘丁醇可用于以下研究：作为一种新的荧光底物用于研究P450eryF的变构机制。基于通过开环聚合用1-芘丁醇进行D,L-乳酸单元的封端而进行荧光聚合物的制备。1-芘丁醇（PB）- 标记的聚(乳酸)（PLA）纳米颗粒（NP）的合成。

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4-(1-芘基)-1-丁醇名称

[ CAS 号 ]:
67000-89-9

[ 中文名 ]:
4-(1-芘基)-1-丁醇

[ 英文名 ]:
1-Pyrenebutanol

[中文别名 ]:

1-芘丁

[英文别名 ]:

1-Pyrenebutanol
4-pyrenylbutan-1-ol
MFCD00192423

4-(1-芘基)-1-丁醇物理化学性质

[ 密度 ]:
1.217g/cm3

[ 沸点 ]:
488.4ºC at 760 mmHg

[ 熔点 ]:
80-83ºC(lit.)

[ 分子式 ]:
C₂₀H₁₈O

[ 分子量 ]:
274.35600

[ 闪点 ]:
205.4ºC

[ 精确质量 ]:
274.13600

[ PSA ]:
20.23000

[ LogP ]:
4.89900

[ 外观性状 ]:
白色至淡棕色粉末

[ 折射率 ]:
1.761

[ 储存条件 ]:
室温

4-(1-芘基)-1-丁醇安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

4-(1-芘基)-1-丁醇合成路线

详细合成路线

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4-(1-芘基)-1-丁醇文献

Immobilization and stretching of 5'-pyrene-terminated DNA on carbon film deposited on electron microscope grid.

Microsc. Res. Tech. 78 , 994-1000, (2015)

The immobilization and stretching of randomly coiled DNA molecules on hydrophobic carbon film is a challenging microscopic technique, which possess various applications, especially for genome sequenci...

Synthesis of a novel fluorescent poly(D,L-lactide) end-capped with 1-pyrenebutanol used for the preparation of nanoparticles.

Eur. J. Pharm. Sci. 20(2) , 217-22, (2003)

A new fluorescent polymer based on D,L-lactic acid units end-capped with 1-pyrenebutanol (PLAP) was synthesized by ring-opening polymerization. PLAP having different molecular weight could be obtained...

Allosteric mechanisms in P450eryF probed with 1-pyrenebutanol, a novel fluorescent substrate.

Biochem. Biophys. Res. Commun. 294(4) , 806-12, (2002)

1-Pyrenebutanol (1-PB) has been used as a new fluorescent substrate for P450eryF to explore the molecular mechanisms of cooperativity. Hydroxylation of 1-PB by P450eryF was detected by both fluorometr...

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