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DL-苹果酸二钠水合物

DL-苹果酸二钠水合物用途

DL-苹果酸钠是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

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DL-苹果酸二钠水合物名称

[ CAS 号 ]:
676-46-0

[ 中文名 ]:
DL-羟基丁二酸二钠水合物

[ 英文名 ]:
Sodium DL-Malate

[中文别名 ]:

[英文别名 ]:

DL-Malic acid disodium salt
Disodium DL-malate
Disodium malate
UNII:2EFF9N315F
Sodium DL-Malate
Butanedioic acid, 2-hydroxy-, sodium salt (1:2)
Hydroxybutanedioic acid disodium salt
MFCD00012466
Butanedioic acid, hydroxy-, disodium salt
disodium 2-hydroxybutanedioate

DL-苹果酸二钠水合物生物活性

[ 描述 ]:

DL-苹果酸钠是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

[ 相关类别 ]:

研究领域 >> 其他

DL-苹果酸二钠水合物物理化学性质

[ 沸点 ]:
306.4ºC at 760 mmHg

[ 熔点 ]:
> 300°C (Lit.)

[ 分子式 ]:
C₄H₄Na₂O₅

[ 分子量 ]:
178.051

[ 闪点 ]:
153.4ºC

[ 精确质量 ]:
177.985413

[ PSA ]:
100.49000

[ 外观性状 ]:
固体;White to Almost white powder to crystal

[ 储存条件 ]:
Store below +30°C.

DL-苹果酸二钠水合物MSDS

详细MSDS(安全技术说明书)

DL-苹果酸二钠水合物毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ON7730000

CHEMICAL NAME :: Malic acid, sodium salt

CAS REGISTRY NUMBER :: 676-46-0

LAST UPDATED :: 199504

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C4-H4-O5.2Na

MOLECULAR WEIGHT :: 178.06

WISWESSER LINE NOTATION :: QV1YQVO &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3500 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - excitement Behavioral - muscle weakness

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 25,467,1925

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JBCHA3 Journal of Biological Chemistry. (428 E. Preston St., Baltimore, MD 21202) V.1- 1905- Volume(issue)/page/year: 28,185,1917 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4709 No. of Facilities: 25 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 2440 (estimated) No. of Female Employees: 1459 (estimated)

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DL-苹果酸二钠水合物安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
ON7730000

[ 海关编码 ]:
2917190090

DL-苹果酸二钠水合物海关

[ 海关编码 ]: 2917190090

[ 中文概述 ]:
2917190090 其他无环多元羧酸. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 对苯二甲酸请注明4-CBA值, 对苯二甲酸请注明P-TL酸值, 对苯二甲酸请注明色度, 对苯二甲酸请注明水分

[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

DL-苹果酸二钠水合物文献

Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with carboxylates.

Bioorg. Med. Chem. Lett. 15 , 573-8, (2005)

A detailed inhibition study of five carbonic anhydrase (CA, EC 4.2.1.1) isozymes with carboxylates including aliphatic (formate, acetate), dicarboxylic (oxalate, malonate), hydroxy/keto acids (l-lacta...

GC/TOFMS analysis of metabolites in serum and urine reveals metabolic perturbation of TCA cycle in db/db mice involved in diabetic nephropathy.

Am. J. Physiol. Renal Physiol. 304(11) , F1317-24, (2013)

Early diagnosis of diabetic nephropathy (DN) is difficult although it is of crucial importance to prevent its development. To probe potential markers and the underlying mechanism of DN, an animal mode...

In vitro reactive oxygen species production by mitochondria from the rabbitfish Siganus fuscessens livers and the effects of Irgarol-1051.

Environ. Toxicol. Pharmacol. 35(2) , 154-60, (2013)

In this study, the mitochondria from the livers of Siganus fuscessens were exposed to the Irgarol-1051with or without respiratory chain inhibitors using succinate or malate as the substrate, and the e...

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