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2-氨基-3-甲基-9H-吡啶[2,3-b]吲哚

2-氨基-3-甲基-9H-吡啶[2,3-b]吲哚名称

[ CAS 号 ]:
68006-83-7

[ 中文名 ]:
2-氨基-3-甲基-9H-吡啶[2,3-b]吲哚

[ 英文名 ]:
2-AMINO-3-METHYL-9H-PYRIDO[2,3-B]INDOLE

[中文别名 ]:

2-氨基-3-甲基-9H-吡啶并[2,3-b]吲哚

[英文别名 ]:

Glob-P-1

2-氨基-3-甲基-9H-吡啶[2,3-b]吲哚物理化学性质

[ 密度 ]:
1.334g/cm3

[ 沸点 ]:
443.2ºC at 760mmHg

[ 熔点 ]:
215-218ºC

[ 分子式 ]:
C₁₂H₁₁N₃

[ 分子量 ]:
197.23600

[ 闪点 ]:
252.1ºC

[ 精确质量 ]:
197.09500

[ PSA ]:
54.70000

[ LogP ]:
3.18790

[ 折射率 ]:
1.806

2-氨基-3-甲基-9H-吡啶[2,3-b]吲哚毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU9354380

CHEMICAL NAME :: 9H-Pyrido(2,3-b)indole, 2-amino-3-methyl-

CAS REGISTRY NUMBER :: 68006-83-7

LAST UPDATED :: 199712

DATA ITEMS CITED :: 19

MOLECULAR FORMULA :: C12-H11-N3

MOLECULAR WEIGHT :: 197.26

WISWESSER LINE NOTATION :: T B656 FN HMJ D1 EZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 420 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 32800 mg/kg/85W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 37380 mg/kg/64W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 35424 mg/kg/70W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors

TYPE OF TEST :: Specific locus test

TYPE OF TEST :: DNA adduct

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 125 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 269,79,1992 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 40,253,1986 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 40,253,1986 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

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2-氨基-3-甲基-9H-吡啶[2,3-b]吲哚安全信息

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
UN 2811

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

[ 海关编码 ]:
2933990090

2-氨基-3-甲基-9H-吡啶[2,3-b]吲哚合成路线

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2-氨基-3-甲基-9H-吡啶[2,3-b]吲哚海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%