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N,N'-二异丙基碳二亚胺

N,N'-二异丙基碳二亚胺用途

【用途一】
主要用作丁胺卡那霉素、谷胱甘肽等药物的脱水剂，也可用于酸酐、醛、酮、异氰酸酯的合成
【用途二】
碳二亚胺类缩合剂，在多肽合成中，替代DCC的作用。所形成的脲副产物在有机溶剂中溶解性较好，较DCC形成的副产物更被容易除去。

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N,N'-二异丙基碳二亚胺名称

[ CAS 号 ]:
693-13-0

[ 中文名 ]:
N,N'-二异丙基碳二亚胺

[ 英文名 ]:
N,N′-diisopropylcarbodiimide

[中文别名 ]:

[英文别名 ]:

2-Propanamine, N,N'-methanetetraylbis-
DIC/DIPCDI
diisopropylcarbodiimide
2-Propanamine, N-[(1-methylethyl)carbonimidoyl]-
N,N'-dipropan-2-ylcarbodiimide
N,N'-bis(1-methylethyl)carbodiimide
DICI
1,3-Diisopropyl carbodiimide
N,N'-diisopropylcarb
DIPCDI

N,N'-二异丙基碳二亚胺物理化学性质

[ 密度 ]:
0.8±0.1 g/cm3

[ 沸点 ]:
146.5±9.0 °C at 760 mmHg

[ 熔点 ]:
210-2120C (dec)

[ 分子式 ]:
C₇H₁₄N₂

[ 分子量 ]:
126.200

[ 闪点 ]:
33.9±0.0 °C

[ 精确质量 ]:
126.115700

[ PSA ]:
24.72000

[ LogP ]:
3.18

[ 外观性状 ]:
无色至淡黄色液体

[ 蒸汽压 ]:
5.8±0.3 mmHg at 25°C

[ 折射率 ]:
1.445

[ 储存条件 ]:
2-8°C

N,N'-二异丙基碳二亚胺MSDS

N,N'-二异丙基碳二亚胺安全信息

[ 符号 ]:

GHS05, GHS06, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H315-H317-H318-H330-H334-H335

[ 警示性声明 ]:
P260-P280-P284-P305 + P351 + P338-P310

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
T+:Verytoxic;

[ 风险声明 (欧洲) ]:
R10;R26;R36/37/38;R41;R42/43

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45-S38-S28A-S16

[ 危险品运输编码 ]:
UN 2929 6.1/PG 1

[ WGK德国 ]:
3

[ RTECS号 ]:
FF2175000

[ 包装等级 ]:
II

[ 危险类别 ]:
6.1

[ 海关编码 ]:
29252000

N,N'-二异丙基碳二亚胺合成路线

N,N'-二异丙基碳二亚胺上下游产品

N,N'-二异丙基碳二亚胺上游产品

N,N'-二异丙基碳二亚胺下游产品

N,N'-二异丙基碳二亚胺海关

[ 海关编码 ]: 2921199090

[ 中文概述 ]:
2921199090 其他无环单胺及其衍生物及其盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

N,N'-二异丙基碳二亚胺文献

LRRK1-phosphorylated CLIP-170 regulates EGFR trafficking by recruiting p150Glued to microtubule plus ends.

J. Cell Sci. 128(2) , 385-96, (2015)

The binding of ligand to epidermal growth factor receptor (EGFR) causes the receptor to become activated and stimulates the endocytosis of EGFR. Early endosomes containing activated EGFR migrate along...

DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity.

J. Exp. Med. 211(13) , 2549-66, (2014)

DOCK8 mutations result in an inherited combined immunodeficiency characterized by increased susceptibility to skin and other infections. We show that when DOCK8-deficient T and NK cells migrate throug...

Incorporation of electrochemical advanced oxidation processes in a multistage treatment system for sanitary landfill leachate.

Water Res. 81 , 375-87, (2015)

The current study has proved the technical feasibility of including electrochemical advanced oxidation processes (EAOPs) in a multistage strategy for the remediation of a sanitary landfill leachate th...

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