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2,3-二甲氧基-1,4-萘醌

2,3-二甲氧基-1,4-萘醌用途

DMNQ 是一种氧化还原循环剂,以浓度依赖性方式在细胞内产生超氧化物和过氧化氢。DMNQ 诱导 ROS 增加。

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2,3-二甲氧基-1,4-萘醌名称

[ CAS 号 ]:
6956-96-3

[ 中文名 ]:
2,3-二甲氧基-1,4-萘醌

[ 英文名 ]:
DMNQ

[英文别名 ]:

MFCD00184331
dmnq
Lopac-D-5439
2,3-dimethoxy-1,4-naphthalenedione
DiMeNQ
2,3-Dimethoxy-1,4-naphthoquinone
2,3-dimethoxy-1,4-naphtoquinone
2,3-Dimethoxynaphthoquinone
2,3-dimethoxy-1,4-NQ

2,3-二甲氧基-1,4-萘醌生物活性

[ 描述 ]:

DMNQ 是一种氧化还原循环剂,以浓度依赖性方式在细胞内产生超氧化物和过氧化氢。DMNQ 诱导 ROS 增加。

[ 相关类别 ]:

研究领域 >> 心血管疾病

信号通路 >> 蛋白酪氨酸激酶 >> ROS

[参考文献]

[1]. Chacko BK, et al. The Bioenergetic Health Index is a sensitive measure of oxidative stress in human monocytes. Redox Biol. 2016 Aug;8:43-50.

2,3-二甲氧基-1,4-萘醌物理化学性质

[ 密度 ]:
1.28g/cm3

[ 沸点 ]:
392.5ºC at 760 mmHg

[ 分子式 ]:
C₁₂H₁₀O₄

[ 分子量 ]:
218.20500

[ 闪点 ]:
177.6ºC

[ 精确质量 ]:
218.05800

[ PSA ]:
52.60000

[ LogP ]:
1.57000

[ 折射率 ]:
1.571

[ 储存条件 ]:
-20°C，密闭，干燥

2,3-二甲氧基-1,4-萘醌MSDS

详细MSDS(安全技术说明书)

2,3-二甲氧基-1,4-萘醌安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2914690090

2,3-二甲氧基-1,4-萘醌海关

[ 海关编码 ]: 2914690090

[ 中文概述 ]:
2914690090 其他醌. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%

[ Summary ]:
2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

2,3-二甲氧基-1,4-萘醌文献

Carvacrol and rosemary essential oil manifest cytotoxic, DNA-protective and pro-apoptotic effect having no effect on DNA repair.

Neoplasma 61(6) , 690-9, (2014)

For several thousand years natural products were successfully used to treat a variety of diseases and to maintain health in humans, but until now it is not fully known what causes these medicinal effe...

Posttranslational Regulation of Human DNA Polymerase ι.

J. Biol. Chem. 290 , 27332-44, (2015)

Human DNA polymerases (pols) η and ι are Y-family DNA polymerase paralogs that facilitate translesion synthesis past damaged DNA. Both polη and polι can be monoubiquitinated in vivo. Polη has been sho...

Hypoxia drives transient site-specific copy gain and drug-resistant gene expression.

Genes Dev. 29 , 1018-31, (2015)

Copy number heterogeneity is a prominent feature within tumors. The molecular basis for this heterogeneity remains poorly characterized. Here, we demonstrate that hypoxia induces transient site-specif...

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