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腺嘌呤磷酸盐

腺嘌呤磷酸盐用途

【用途一】
用于防治各种原因引起的白细胞减少症，特别是用于肿瘤化学治疗时引起的白细胞减少症
【用途二】
有刺激性白细胞增生作用。用于各种原因引起的白细胞减少症，特别是由于肿瘤化疗、放射治疗以及苯类等药物中毒所造成的白细胞减少症。

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腺嘌呤磷酸盐名称

[ CAS 号 ]:
70700-30-0

[ 中文名 ]:
腺嘌呤磷酸盐

[ 英文名 ]:
6-Aminopurine phosphate

[中文别名 ]:

[英文别名 ]:

9H-purin-6-amine, phosphate (1:1)
VITAMIN A PALMITIAT
MFCD00035170
6-Aminopurine phosphate
EINECS 257-702-7
1H-Purin-6-amine phosphate (1:1)
7H-Purin-6-amine, phosphate (1:1)
Aminopurine phosphate
Adeniniumphosphat
9H-Purin-6-amine phosphate (1:1)

腺嘌呤磷酸盐物理化学性质

[ 沸点 ]:
553.5ºC at 760 mmHg

[ 熔点 ]:
261-263ºC

[ 分子式 ]:
C₅H₅N₅

[ 分子量 ]:
233.122

[ 闪点 ]:
322.7ºC

[ 精确质量 ]:
233.031387

[ PSA ]:
80.48000

[ LogP ]:
0.51630

[ 外观性状 ]:
白色结晶粉末

[ 储存条件 ]:
室温

腺嘌呤磷酸盐安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
22

[ 安全声明 (欧洲) ]:
S36

[ 危险品运输编码 ]:
NONH for all modes of transport

腺嘌呤磷酸盐制备

【方法一】
腺嘌呤成盐而得。将腺嘌呤加入蒸馏水中，加热至沸，搅拌加磷酸至pH1-2，使全溶，加活性炭脱色0.5h，过滤，再重复脱色一次，滤液冷却结晶，过滤，结晶用蒸馏水洗涤，再用乙醇洗涤一次。干燥，得腺嘌呤磷酸盐(维生素B4)。谷氨酸发酵生产过程副产腺嘌呤。采用×7阳离子交换树脂吸附谷氨酸母液，收集洗脱液pH7-12部分，酸化滤除杂质，再以001×7树脂吸附，0.2N氢氧化钠洗脱，浓缩，结晶得腺嘌呤粗品。加水溶解，磷酸调pH 1-2，脱色，过滤，得腺嘌呤磷酸盐粗品。再经结晶，精制，干燥得维生素B4。

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腺嘌呤磷酸盐文献

Disturbed Hsp70 and Hsp27 expression and thiol redox status in porcine kidney PK15 cells provoked by individual and combined ochratoxin A and citrinin treatments.

Food Chem. Toxicol. 71 , 97-105, (2014)

The aim of this study was to explore the oxidative properties of ochratoxin A (OTA) and citrinin (CTN) as a possible underlying mechanism of their individual and/or combined cytotoxicity. Metabolic ac...

Vegetables' juice influences polyol pathway by multiple mechanisms in favour of reducing development of oxidative stress and resultant diabetic complications.

Pharmacogn. Mag. 10(Suppl 2) , S383-91, (2014)

Hyperglycemia induced generation of free radicals and consequent development of oxidative stress by polyol pathway is one of the crucial mechanisms stirring up development of diabetic complications. W...

The traditional drug Gongjin-Dan ameliorates chronic fatigue in a forced-stress mouse exercise model.

J. Ethnopharmacol. 168 , 268-78, (2015)

Gongjin-Dan is a representative traditional Oriental medicine herbal drug that has been used to treat chronic fatigue symptoms for several hundred years. We evaluated the anti-fatigue effects of Gongj...

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腺嘌呤磷酸盐

腺嘌呤磷酸盐用途

腺嘌呤磷酸盐名称

腺嘌呤磷酸盐物理化学性质

腺嘌呤磷酸盐安全信息

腺嘌呤磷酸盐制备

腺嘌呤磷酸盐文献

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