腺嘌呤硫酸盐

腺嘌呤硫酸盐用途

Adenine hemisulfate (6-Aminopurine hemisulfate) 是嘌呤衍生物,在生物化学中具有多种作用,在生物化学中具有多种作用,包括细胞呼吸、高能量的 ATP 和辅酶因子 NAD 和 FAD 的形成、蛋白质合成,以及作为 DNA 和 RNA 的化学成分。

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腺嘌呤硫酸盐名称

[ CAS 号 ]:
321-30-2

[ 中文名 ]:
硫酸腺嘌呤

[ 英文名 ]:
Adenine hemisulfate

[中文别名 ]:

[英文别名 ]:

diadenine sulphate
Adenine Sulfate Dihydrate
6-Aminopurine hemisulfate salt
9H-Purin-6-amine sulfate (2:1)
EINECS 206-286-5
Bis(6-amino-9H-purin-1-ium) sulfate
denine,sulfate
Adenine sulfate salt
VITAMIN B SULFATE
Adenine sulfate

腺嘌呤硫酸盐生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 癌症

信号通路 >> 细胞周期/DNA损伤 >> DNA/RNA合成

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Reader V. The assay of vitamin B(4). Biochem J. 1930;24(6):1827-31.

[2]. ORO J, et al. Synthesis of purines under possible primitive earth conditions. I. Adenine from hydrogen cyanide. Arch Biochem Biophys. 1961 Aug;94:217-27.

腺嘌呤硫酸盐物理化学性质

[ 沸点 ]:
553.5ºC at 760mmHg

[ 熔点 ]:
285 °C (dec.)(lit.)

[ 分子式 ]:
C₅H₇N₅O₄S

[ 分子量 ]:
368.332

[ 精确质量 ]:
368.076355

[ PSA ]:
243.94000

[ LogP ]:
1.46060

[ 外观性状 ]:
白色至淡黄色晶体粉末

[ 储存条件 ]:
Store at RT.

[ 水溶解性 ]:
0.4 g/100 mL

腺嘌呤硫酸盐MSDS

详细MSDS(安全技术说明书)

腺嘌呤硫酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU7140000

CAS REGISTRY NUMBER :: 321-30-2

LAST UPDATED :: 199709

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C5-H5-N5.1/2H2-O4-S

MOLECULAR WEIGHT :: 821.71

WISWESSER LINE NOTATION :: T56 BM DN FN HNJ IZ &..H2.S-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 232,302,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 750 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Behavioral - ataxia Lungs, Thorax, or Respiration - other changes

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 47,229,1979 *** REVIEWS *** TOXICOLOGY REVIEW ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,24,1957 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83237 No. of Facilities: 59 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 588 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83237 No. of Facilities: 496 (estimated) No. of Industries: 2 No. of Occupations: 8 No. of Employees: 5574 (estimated) No. of Female Employees: 2982 (estimated)

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腺嘌呤硫酸盐安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 警示性声明 ]:
P301 + P312 + P330

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
AU7140000

[ 海关编码 ]:
2933990090

腺嘌呤硫酸盐海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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