Nafimidone

Nafimidone名称

[ CAS 号 ]:
70891-37-1

[ 英文名 ]:
Nafimidone

[英文别名 ]:

Nafimidone hydrochloride (USAN)
2-(1-Imidazolylacetyl)naphthalene hydrochloride
2'-ACETONAPHTHONE,2-(1-IMIDAZOLYL)-,HYDROCHLORIDE
Nafimidone HCl
1-(2-Naphthoylmethyl)imidazole hydrochloride
Nafimidone hydrochloride

Nafimidone物理化学性质

[ 分子式 ]:
C₁₅H₁₃ClN₂O

[ 分子量 ]:
272.73000

[ 精确质量 ]:
272.07200

[ PSA ]:
34.89000

[ LogP ]:
3.72120

Nafimidone毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KM5780880

CHEMICAL NAME :: Ethanone, 2-(1H-imidazol-1-yl)-1-(2-naphthalenyl)-, monohydrochloride

CAS REGISTRY NUMBER :: 70891-37-1

LAST UPDATED :: 199203

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C15-H12-N2-O.Cl-H

MOLECULAR WEIGHT :: 272.75

WISWESSER LINE NOTATION :: L66J BV1- AT5N CNJ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 504 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 29,1577,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 420 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 120,185,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 210 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 120,185,1981

点击显示

Nafimidone安全信息

[ 海关编码 ]:
2934999090

Nafimidone合成路线

详细合成路线

Nafimidone上下游产品

Nafimidone上游产品

Nafimidone下游产品

Nafimidone海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%