乙滴涕

乙滴涕用途

Perthane is the diethyl derivative of common pesticide DDD. It may prevent the formation of spontaneous mammary carcinoma, and also may causes adrenocortical atrophy in humans.

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乙滴涕名称

[ CAS 号 ]:
72-56-0

[ 中文名 ]:
乙滴涕

[ 英文名 ]:
Perthane

[中文别名 ]:

[英文别名 ]:

MFCD00045254
1,1-bis-(4-ethyl-phenyl)-2,2-dichloro-ethane
Ethylan
EINECS 200-785-1
Caswell No. 337
1,1-di-(p-ethylphenyl)-2,2-dichloroethane
p,p'-Ethyl DDD
1,1-dichloro-2,2-bis(p-ethylphenyl)-ethane
1,1’-(2,2-dichloroethylidene)bis[4-ethylbenzene]
Perthan

乙滴涕物理化学性质

[ 密度 ]:
1.117 g/cm3

[ 沸点 ]:
407.2ºC at 760 mmHg

[ 熔点 ]:
56-57℃ (methanol )

[ 分子式 ]:
C₁₈H₂₀Cl₂

[ 分子量 ]:
307.25700

[ 闪点 ]:
212.1ºC

[ 精确质量 ]:
306.09400

[ LogP ]:
5.74700

[ 折射率 ]:
1.56

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

乙滴涕MSDS

乙滴涕毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KH5790000

CHEMICAL NAME :: Ethane, 2,2-bis(p-ethylphenyl)-1,1-dichloro-

CAS REGISTRY NUMBER :: 72-56-0

BEILSTEIN REFERENCE NO. :: 2054366

LAST UPDATED :: 199710

DATA ITEMS CITED :: 15

MOLECULAR FORMULA :: C18-H20-Cl2

MOLECULAR WEIGHT :: 307.28

WISWESSER LINE NOTATION :: GYGYR D2&R D2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 73 mg/kg

TOXIC EFFECTS :: Behavioral - tremor

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 173 mg/kg

TOXIC EFFECTS :: Behavioral - tremor

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - wild bird species

DOSE/DURATION :: 9 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 210 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 547 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 900 mg/kg

SEX/DURATION :: female 6-14 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord)

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 333 ug/plate

REFERENCE :: NTPTB* NTP Technical Bulletin. (National Toxicology Program, Landow Bldg. 3A-06, 7910 Woodmont Ave., Bethesda, MD 20205) Volume(issue)/page/year: APR1982 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83493 No. of Facilities: 1274 (estimated) No. of Industries: 2 No. of Occupations: 4 No. of Employees: 10159 (estimated)

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乙滴涕安全信息

[ 符号 ]:

GHS09

[ 信号词 ]:
Warning

[ 危害声明 ]:
H410

[ 警示性声明 ]:
P273-P501

[ 个人防护装备 ]:
Eyeshields;Gloves

[ 危害码 (欧洲) ]:
N: Dangerous for the environment;

[ 风险声明 (欧洲) ]:
50/53

[ 安全声明 (欧洲) ]:
S60-S61

[ 危险品运输编码 ]:
UN 2761

[ RTECS号 ]:
KH5790000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

[ 海关编码 ]:
2903999090

乙滴涕合成路线

乙滴涕上下游产品

乙滴涕上游产品

乙滴涕下游产品

乙滴涕海关

[ 海关编码 ]: 2903999090

[ 中文概述 ]:
2903999090 其他芳烃卤化衍生物. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

乙滴涕文献

Development of QSAR models for predicting hepatocarcinogenic toxicity of chemicals.

Eur. J. Med. Chem. 44 , 3658-64, (2009)

A dataset comprising 55 chemicals with hepatocarcinogenic potency indices was collected from the Carcinogenic Potency Database with the aim of developing QSAR models enabling prediction of the above u...

Potential compounds for monitoring method performance in the determination of selected organochlorine pesticides and polychlorinated biphenyls in human serum.

J. Anal. Toxicol. 14(3) , 143-5, (1990)

Four compounds--2,2', 3,4'-tetrachlorobiphenyl, decachlorodiphenylether, 1,1-dichloro-2,2-bis(p-ethylphenyl)ethane, and dichlorobenzophenone--are recommended for monitoring the within-sample behavior ...

Rapid decline of persistent organochlorine pollutants in serum among young Swedish males.

Chemosphere 70(9) , 1620-8, (2008)

To investigate a possible time trend in serum concentrations of persistent organochlorine pollutants (POPs), representative samples of the young (median age 18 years) Swedish male population were inve...

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乙滴涕