β-富纳曲胺盐酸盐

β-富纳曲胺盐酸盐名称

[ 英文名 ]:
β-Funaltrexamine hydrochloride,(E)-4-[[5α,6β)-17-Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-yl]amino]-4-oxo-2-butenoicacidmethylesterhydrochloride

[中文别名 ]:

[英文别名 ]:

b-FunaltrexamineHCl

β-富纳曲胺盐酸盐物理化学性质

[ 沸点 ]:
695.2ºC at 760 mmHg

[ 分子式 ]:
C₂₅H₃₁ClN₂O₆

[ 分子量 ]:
490.97600

[ 闪点 ]:
374.2ºC

[ 精确质量 ]:
490.18700

[ PSA ]:
108.33000

[ LogP ]:
2.30110

β-富纳曲胺盐酸盐MSDS

详细MSDS(安全技术说明书)

β-富纳曲胺盐酸盐安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

β-富纳曲胺盐酸盐文献

Novel orally available salvinorin A analog PR-38 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome.

J. Pharmacol. Exp. Ther. 350(1) , 69-78, (2014)

The opioid and cannabinoid systems play a crucial role in multiple physiological processes in the central nervous system and in the periphery. Selective opioid as well as cannabinoid (CB) receptor ago...

Activation of the cloned human kappa opioid receptor by agonists enhances [35S]GTPgammaS binding to membranes: determination of potencies and efficacies of ligands.

J. Pharmacol. Exp. Ther. 282 , 676, (1997)

Activation of kappa receptors inhibits adenylate cyclase, enhances K+ conductance and reduces Ca++ conductance via pertussis toxin-sensitive G proteins. We recently cloned a human kappa opioid recepto...

Activation of phosphatidylinositol 3-kinase/Akt-mammalian target of Rapamycin signaling pathway in the hippocampus is essential for the acquisition of morphine-induced place preference in rats.

Neuroscience 171(1) , 134-43, (2010)

Hippocampus is a critical structure for the acquisition of morphine-induced conditioned place preference (CPP), which is a usual learning paradigm for assessing drug reward. However, the precise mecha...

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