neplanocin A

neplanocin A用途

()-Neplanocin A potently and irreversibly inactivates SAH hydrolase .It has antitumor activity against mouse leukemia L1210 cells and broad-spectrum antiviral activity.

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neplanocin A名称

[ CAS 号 ]:
72877-50-0

[ 英文名 ]:
neplanocin A

[英文别名 ]:

Neoplanocin A
neplanocin A

neplanocin A物理化学性质

[ 密度 ]:
1.9±0.1 g/cm3

[ 沸点 ]:
632.6±65.0 °C at 760 mmHg

[ 分子式 ]:
C₁₁H₁₃N₅O₃

[ 分子量 ]:
263.253

[ 闪点 ]:
336.4±34.3 °C

[ 精确质量 ]:
263.101837

[ PSA ]:
130.31000

[ LogP ]:
-0.31

[ 蒸汽压 ]:
0.0±2.0 mmHg at 25°C

[ 折射率 ]:
1.882

[ 储存条件 ]:
-20°C，密闭，干燥

neplanocin A毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GY5976500

CHEMICAL NAME :: 3-Cyclopentene-1,2-diol, 3-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-, (1R,2S,3R,5R)-

CAS REGISTRY NUMBER :: 72877-50-0

LAST UPDATED :: 199312

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C11-H13-N5-O3

MOLECULAR WEIGHT :: 263.29

WISWESSER LINE NOTATION :: T56 BN DN FN HNJ IZ D- CL5UTJ A1Q DQ EQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 13700 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - rabbit Kidney

DOSE/DURATION :: 8400 ug/L

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 38,1771,1989

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neplanocin A安全信息

[ 海关编码 ]:
2933990090

neplanocin A合成路线

详细合成路线

neplanocin A上下游产品

neplanocin A上游产品

neplanocin A下游产品

neplanocin A海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%