L-亮氨酸β-萘酰胺

L-亮氨酸β-萘酰胺用途

A small molecule inhibitor of PP2C that activates extensive 3' cleavage at a concentration 50-fold below that required by fluoride or CP..

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L-亮氨酸β-萘酰胺名称

[ CAS 号 ]:
732-85-4

[ 中文名 ]:
L-亮氨酸-β-萘基胺

[ 英文名 ]:
NCI-83633

[英文别名 ]:

H-LEU-BETANA
LEUCINE-BETANA
H-Leu-bNA
L-Leucin-[2]naphthylamid
L-Leu-NNap
L-LEUCINE-2-NAPHTHYLAMIDE
EINECS 211-990-0
MFCD00055914

L-亮氨酸β-萘酰胺物理化学性质

[ 密度 ]:
1.128 g/cm3

[ 沸点 ]:
467ºC at 760 mmHg

[ 分子式 ]:
C₁₆H₂₀N₂O

[ 分子量 ]:
256.34300

[ 闪点 ]:
236.2ºC

[ 精确质量 ]:
256.15800

[ PSA ]:
55.12000

[ LogP ]:
3.92500

[ 外观性状 ]:
固体

[ 折射率 ]:
1.625

[ 储存条件 ]:
20°C

L-亮氨酸β-萘酰胺安全信息

[ 符号 ]:

GHS08

[ 信号词 ]:
Warning

[ 危害声明 ]:
H351

[ 警示性声明 ]:
P281

[ 个人防护装备 ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R40

[ 安全声明 (欧洲) ]:
22-36

[ 危险品运输编码 ]:
NONH for all modes of transport

L-亮氨酸β-萘酰胺合成路线

详细合成路线

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L-亮氨酸β-萘酰胺文献

[Changes in the aminopeptidase activity in the brain neurons of rats subjected long-term to alcoholic intoxication].

Tsitologiia 32(10) , 1006-9, (1990)

A histochemical investigation was made of aminopeptidase activities using L-leucine-beta-naphthylamide and D, L-alanine-beta-naphthylamine as respective substrates in the rat's sensomotor cortex neuro...

Subcellular distribution of soluble and membrane-bound Leu-, Arg- and Asp-beta-naphthylamide-hydrolysing activities in rat brain.

Cell Mol. Biol. 36(2) , 175-9, (1990)

Subcellular distribution of soluble and membrane-bound Leu-, Arg- and Asp-beta-naphthylamide hydrolysing activities (arylamidase activity) was studied from left and right rat brains, each including he...

The aminopeptidase N-encoding pepN gene of Streptomyces lividans 66.

Gene 141(1) , 115-9, (1994)

The gene (pepN) encoding an aminopeptidase N (PepN) has been cloned from Streptomyces lividans. This was done using either leucine-beta-naphthylamide or arginine-beta-naphthylamide in a liquid overlay...

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