L-亮氨酸β-萘酰胺
L-亮氨酸β-萘酰胺结构式
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常用名 | L-亮氨酸β-萘酰胺 | 英文名 | NCI-83633 |
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| CAS号 | 732-85-4 | 分子量 | 256.34300 | |
| 密度 | 1.128 g/cm3 | 沸点 | 467ºC at 760 mmHg | |
| 分子式 | C16H20N2O | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 236.2ºC | |
| 符号 |
GHS08 |
信号词 | Warning |
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[Changes in the aminopeptidase activity in the brain neurons of rats subjected long-term to alcoholic intoxication].
Tsitologiia 32(10) , 1006-9, (1990) A histochemical investigation was made of aminopeptidase activities using L-leucine-beta-naphthylamide and D, L-alanine-beta-naphthylamine as respective substrates in the rat's sensomotor cortex neurons during the period of ethanol withdrawal after a prolonge... |
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Subcellular distribution of soluble and membrane-bound Leu-, Arg- and Asp-beta-naphthylamide-hydrolysing activities in rat brain.
Cell Mol. Biol. 36(2) , 175-9, (1990) Subcellular distribution of soluble and membrane-bound Leu-, Arg- and Asp-beta-naphthylamide hydrolysing activities (arylamidase activity) was studied from left and right rat brains, each including hemisphere, cerebellum and brain stem. Both soluble Leu- and ... |
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The aminopeptidase N-encoding pepN gene of Streptomyces lividans 66.
Gene 141(1) , 115-9, (1994) The gene (pepN) encoding an aminopeptidase N (PepN) has been cloned from Streptomyces lividans. This was done using either leucine-beta-naphthylamide or arginine-beta-naphthylamide in a liquid overlayer on colonies growing on agar medium to screen for overpro... |
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Angiotensin AT4 ligands are potent, competitive inhibitors of insulin regulated aminopeptidase (IRAP).
J. Neurochem. 86(2) , 344-50, (2003) Angiotensin IV (Ang IV) exerts profound effects on memory and learning, a phenomenon ascribed to its binding to a specific AT4 receptor. However the AT4 receptor has recently been identified as the insulin-regulated aminopeptidase (IRAP). In this study, we de... |
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Mode of action towards oligopeptides and proteins of hydrolase H, a high-molecular-weight aminoendopeptidase from rabbit skeletal muscle.
Eur. J. Biochem. 137(1-2) , 23-7, (1983) The mode of action towards oligopeptides and proteins of hydrolase H purified from rabbit skeletal muscle was studied. The presence of protamine or alpha-N-benzoylarginine p-nitroanilide (an endopeptidase substrate) changed both the Km and V values of the enz... |
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Proteolytic activity in the placenta, decidua and postimplantation embryos of the rat.
Isr. J. Med. Sci. 21(4) , 394-6, (1985)
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Abrupt induction of a membrane digestive enzyme by its intraintestinal substrate.
Science 227(4682) , 70-2, (1985) The regulation of amino-oligopeptidase (AOP), an intestinal brush border hydrolase essential for the surface digestion of peptide nutrients, was examined in rats in vivo. Short-term (30-minute) intraintestinal perfusion of a tetrapeptide substrate, Gly-Leu-Gl... |
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Characterization of a neutral aminoacyl-peptide hydrolase from Naegleria fowleri.
J. Protozool. 34(2) , 146-9, (1987) An intracellular alpha-aminoacyl-peptide hydrolase (EC 3.4.11.-) from Naegleria fowleri nN68 (ATCC 30894) has been characterized. The enzyme preparation hydrolyzed phenylalanyl-, tyrosyl-, leucyl-, arginyl-, alanyl-, tryptophanyl-, histidyl-, methionyl-, and ... |
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Regional distribution of neuropeptide-degrading enzyme activity in the rat brain: effects of subacute exposure to carbon disulfide.
J. Biochem. Toxicol. 7(3) , 171-5, (1992) Carbon disulfide, a volatile solvent, is widely used in industry. It has been demonstrated that it causes several neuropsychological symptoms. However, the neurochemical basis of its neurotoxic effect is relatively unknown. In this paper we have measured the ... |
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Aminopeptidase activity is asymmetrically distributed in selected zones of rat brain.
Life Sci. 43(11) , 935-9, (1988) Levels of soluble aminopeptidase (AP), measured as arylamidase activity using L-Leucine-2-Naphthylamide (Leu-2-NA) as substrate, were determined in the soluble fraction of eleven zones of rat brain. Results showed that AP activity is asymmetrically distribute... |