S(+)-4-氨基己烯酸

S(+)-4-氨基己烯酸用途

γ-Vigabatrin has the potential to treat infantile spasms and seizures. It exhibits therapeutic effects against cocaine and other addictions.

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S(+)-4-氨基己烯酸名称

[ CAS 号 ]:
74046-07-4

[ 中文名 ]:
S(+)-4-氨基己烯酸

[ 英文名 ]:
S(+)-4-Aminohexenoic acid

[英文别名 ]:

(S)-4-aminohex-5-enoic acid
(4S)-4-Aminohex-5-enoic acid
(4S)-4-Amino-5-hexenoic acid
S(+)-|A-Vigabatrin
5-Hexenoic acid,4-amino-,(+)
4-amino-5-hexenoic acid
(S)-vigabatrin(R)
S(+)-4-Aminohexenoic acid
(S)-Vigabatrin
(S)-4-Amino-5-hexenoic Acid

S(+)-4-氨基己烯酸物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
277.7±28.0 °C at 760 mmHg

[ 熔点 ]:
166 - 167 °C

[ 分子式 ]:
C₆H₁₁NO₂

[ 分子量 ]:
129.157

[ 闪点 ]:
121.7±24.0 °C

[ 精确质量 ]:
129.078979

[ PSA ]:
63.32000

[ LogP ]:
-0.10

[ 外观性状 ]:
灰白色或米色固体

[ 蒸汽压 ]:
0.0±1.2 mmHg at 25°C

[ 折射率 ]:
1.483

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
Soluble to 100 mM in water

S(+)-4-氨基己烯酸MSDS

S(+)-4-氨基己烯酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

S(+)-4-氨基己烯酸合成路线

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S(+)-4-氨基己烯酸文献

Differential effect of gamma-vinyl GABA and valproate on GABA-transaminase from cultured neurones and astrocytes.

Neuropharmacology 25 , 617-625, (1986)

A preferential effect of valproate on gamma-aminobutyric acid (GABA) in the nerve terminal compartment has been proposed. Gamma-vinyl GABA, an irreversible inhibitor of GABA-transaminase (GABA-T) caus...

An analysis of the cortical and striatal involvement in dyskinesia induced in rats by intracerebral injection of GABA-transaminase inhibitors and picrotoxin.

Eur. J. Pharmacol. 62 , 319, (1980)

Unilateral intrastriatal injection of various substances induces a characteristic dyskinetic syndrome in rats. These substances include picrotoxin as well as a series of irreversible GABA-transaminase...

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