< 生产厂家价格 >

DL-4-氯苯基丙氨酸

DL-4-氯苯基丙氨酸用途

Fenclonine 是一种医药中间体。

点击显示

DL-4-氯苯基丙氨酸名称

[ CAS 号 ]:
7424-00-2

[ 中文名 ]:
DL-4-氯苯丙氨酸

[ 英文名 ]:
DL-4-Chlorophenylalanine

[中文别名 ]:

[英文别名 ]:

L-4-Chlorophenylalanine
para-Chlorophenylalanine
2-amino-3-(4-chlorophenyl)propanoic acid
PCP,PCPA
p-Cl-L-Phe-OH
p-Chloro-L-phenylalanine
H-DL-PHE(4-CL)-OH
EINECS 231-051-9
4-Chlorophenylalanine
fenchlonine

DL-4-氯苯基丙氨酸生物活性

[ 描述 ]:

Fenclonine 是一种医药中间体。

[ 相关类别 ]:

信号通路 >> 代谢酶/蛋白酶 >> 色氨酸羟化酶

研究领域 >> 其他

[相关活性小分子]

Telotristat | 4-[2-氨基-6-[(1R)-2,2,2-三氟-1-(3'-甲氧基联苯-4-基)乙氧基]嘧啶-4-基]-L-苯丙氨酸 | LP-533401

DL-4-氯苯基丙氨酸物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
339.5±32.0 °C at 760 mmHg

[ 熔点 ]:
>240 °C (dec.)(lit.)

[ 分子式 ]:
C₉H₁₀ClNO₂

[ 分子量 ]:
199.634

[ 闪点 ]:
159.1±25.1 °C

[ 精确质量 ]:
199.040009

[ PSA ]:
63.32000

[ LogP ]:
1.71

[ 外观性状 ]:
白色固体

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.590

[ 储存条件 ]:
−20°C

[ 水溶解性 ]:
slightly soluble

DL-4-氯苯基丙氨酸MSDS

DL-4-氯苯基丙氨酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AY4390010

CHEMICAL NAME :: Alanine, 3-(p-chlorophenyl)-, DL-

CAS REGISTRY NUMBER :: 7424-00-2

BEILSTEIN REFERENCE NO. :: 2805758

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H10-Cl-N-O2

MOLECULAR WEIGHT :: 199.65

WISWESSER LINE NOTATION :: QVYZ1R DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 1794 mg/kg

SEX/DURATION :: female 14-19 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

REFERENCE :: BIMDA2 Biochemical Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1967- Volume(issue)/page/year: 4,516,1970

点击显示

DL-4-氯苯基丙氨酸安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301-H317

[ 警示性声明 ]:
P280-P301 + P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T:Toxic;

[ 风险声明 (欧洲) ]:
R25;R43

[ 安全声明 (欧洲) ]:
S36/37-S45

[ 危险品运输编码 ]:
UN 2811 6.1/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
AY4390010

[ 海关编码 ]:
2922499990

DL-4-氯苯基丙氨酸合成路线

DL-4-氯苯基丙氨酸上下游产品

DL-4-氯苯基丙氨酸上游产品

DL-4-氯苯基丙氨酸下游产品

DL-4-氯苯基丙氨酸海关

[ 海关编码 ]: 2922499990

[ 中文概述 ]:
2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

DL-4-氯苯基丙氨酸文献

Inhibitory Effect of Dried Pomegranate Concentration Powder on Melanogenesis in B16F10 Melanoma Cells; Involvement of p38 and PKA Signaling Pathways.

Int. J. Mol. Sci. 16 , 24219-42, (2015)

Plants rich in antioxidant substances may be useful for preventing skin aging. Pomegranates, containing flavonoids and other polyphenolic compounds, are widely consumed due to their beneficial propert...

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...

The natural basil flavonoid nevadensin protects against a methyleugenol-induced marker of hepatocarcinogenicity in male F344 rat.

Food Chem. Toxicol. 74 , 28-34, (2014)

The alkenylbenzene methyleugenol occurs naturally in a variety of spices and herbs, including basil, and their essential oils. At high dose levels methyleugenol induces hepatocarcinogenicity in rodent...

更多文献