6-硝基联苯

6-硝基联苯名称

[ CAS 号 ]:
7496-02-8

[ 中文名 ]:
6-硝基联苯

[ 英文名 ]:
Chrysene, 6-nitro-

[中文别名 ]:

6-硝基屈

[英文别名 ]:

6-nitrochrysene
MFCD00021179

6-硝基联苯物理化学性质

[ 密度 ]:
1.342g/cm3

[ 沸点 ]:
505ºC at 760 mmHg

[ 熔点 ]:
220ºC (dec.)(lit.)

[ 分子式 ]:
C₁₈H₁₁NO₂

[ 分子量 ]:
273.28500

[ 闪点 ]:
252.5ºC

[ 精确质量 ]:
273.07900

[ PSA ]:
45.82000

[ LogP ]:
5.57760

[ 折射率 ]:
1.791

[ 储存条件 ]:
2-8°C

6-硝基联苯MSDS

详细MSDS(安全技术说明书)

6-硝基联苯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GC1930000

CHEMICAL NAME :: Chrysene, 6-nitro-

CAS REGISTRY NUMBER :: 7496-02-8

BEILSTEIN REFERENCE NO. :: 2134652

LAST UPDATED :: 199612

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C18-H11-N-O2

MOLECULAR WEIGHT :: 273.30

WISWESSER LINE NOTATION :: L E6 B666J DNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 9163 ug/kg/2W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors

TYPE OF TEST :: Micronucleus test

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 10 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 279,153,1992 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 46,267,1989 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 46,267,1989 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 46,267,1989

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6-硝基联苯安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302 + H312 + H332-H340-H350

[ 警示性声明 ]:
P201-P261-P280-P301 + P312 + P330-P308 + P313

[ 个人防护装备 ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T

[ 风险声明 (欧洲) ]:
45-46-20/21/22

[ 安全声明 (欧洲) ]:
S22;S45;S53;S36/S37/S39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
GC1930000

6-硝基联苯上下游产品

6-硝基联苯上游产品

6-硝基联苯下游产品

6-硝基联苯文献

Polycyclic nitroarenes (nitro-PAHs) as biomarkers of exposure to diesel exhaust.

Mutat. Res. 441(1) , 135-44, (1999)

Diesel exhaust contains numerous genotoxic carcinogens. It is essentially unknown to which extent this source contributes to the total load of these chemicals in humans. One possible approach to the p...

Synthesis of anti-1,2-dihydroxy-3,4-epoxy-1,2,3, 4-tetrahydro-6-nitrochrysene and its reaction with 2'-deoxyguanosine- 5'-monophosphate, 2'-deoxyadenosine-5'-monophosphate, and calf thymus DNA in vitro.

Chem. Res. Toxicol. 13(11) , 1143-8, (2000)

The remarkable carcinogenic activity of 6-nitrochrysene (6-NC) in several animal models, and its environmental presence, suggest its potential importance with regard to human cancer development. Depen...

Genomic DNA sequencing of mRNA splicing mutants in the hprt gene of Chinese hamster ovary cells.

Environ. Mol. Mutagen. 25(2) , 85-96, (1995)

We have analyzed 41 mRNA-splicing mutants from the hypoxanthine-guanine phosphoribosyl-transferase (hprt) gene of Chinese hamster ovary (CHO) cells. Twenty-two of these mutants produced single cDNA PC...

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