AI-1

AI-1用途

Nrf2 acticatior AI-1 is a small-molecule inducer of the antioxidant response element (ARE) that activates and stabilizes Nrf2 by covalently modifying Keap1, activates an ARE-dependent luciferase reporter with an EC50 of 2.7 uM.

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AI-1名称

[ CAS 号 ]:
75483-04-4

[ 英文名 ]:
AI-1

[英文别名 ]:

ARE inducer-1
antioxidant response element inducer-1

AI-1物理化学性质

[ 密度 ]:
1.34g/cm3

[ 沸点 ]:
358.7ºC at 760 mmHg

[ 分子式 ]:
C₁₃H₁₂ClNO₃

[ 分子量 ]:
265.69200

[ 闪点 ]:
170.7ºC

[ 精确质量 ]:
265.05100

[ PSA ]:
48.30000

[ LogP ]:
2.36860

[ 折射率 ]:
1.597

AI-1MSDS

详细MSDS(安全技术说明书)

AI-1安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H317

[ 警示性声明 ]:
P280

[ 危险品运输编码 ]:
NONH for all modes of transport

AI-1合成路线

详细合成路线

AI-1文献

Genome-wide RNA sequencing analysis of quorum sensing-controlled regulons in the plant-associated Burkholderia glumae PG1 strain.

Appl. Environ. Microbiol. 81 , 7993-8007, (2015)

Burkholderia glumae PG1 is a soil-associated motile plant-pathogenic bacterium possessing a cell density-dependent regulation system called quorum sensing (QS). Its genome contains three genes, here d...

Involvement of luxS in Biofilm Formation by Capnocytophaga ochracea.

PLoS ONE 11 , e0147114, (2016)

Capnocytophaga ochracea is present in the dental plaque biofilm of patients with periodontitis. Biofilm cells change their phenotype through quorum sensing in response to fluctuations in cell-populati...

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