乙酰柠檬酸三丁酯

乙酰柠檬酸三丁酯用途

【用途一】
用于乳制品、饮料、食品等包装材料所用的无毒增塑剂
【用途二】
该产品是无毒无味安全增塑剂，其而热性、耐寒性、耐光性和耐水性能优良。适用于食品包装、儿童玩具、医用制品等领域。美国F.D.A批准用于肉食品包装材料及玩具用料。由于本品优良的性能，大量用于新鲜肉类及其制品的包装、乳制品包装、聚氯乙烯医用制品、口香糖等。树脂经本品增塑后呈现良好的透明度和低温挠曲性能，并在不同介质中具有低挥发性和抽出率，在溶封时对热稳定，不变色。

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乙酰柠檬酸三丁酯名称

[ CAS 号 ]:
77-90-7

[ 中文名 ]:
乙酰柠檬酸三丁酯

[ 英文名 ]:
Tributyl citrate acetate

[中文别名 ]:

[英文别名 ]:

Tributyl O-Acetylcitrate
MFCD00043554
EINECS 201-067-0
Citroflex A
tributyl acetylcitrate
UNII-0ZBX0N59RZ
4OV1XVO4&OV1&1OV4
Acetyl tri-n-butyl citrate
ATBC
Tributyl 2-acetoxypropane-1,2,3-tricarboxylate

乙酰柠檬酸三丁酯生物活性

[ 描述 ]:

Acetyl tributyl citrate (Tributyl O-acetylcitrate; ATBC) 是一种替代增塑剂。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Andreia Alves, et al. Case Study on Screening Emerging Pollutants in Urine and Nails. Environ Sci Technol. 2017 Apr 4;51(7):4046-4053.

乙酰柠檬酸三丁酯物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
418.1±40.0 °C at 760 mmHg

[ 熔点 ]:
-59 °C

[ 分子式 ]:
C₂₀H₃₄O₈

[ 分子量 ]:
402.479

[ 闪点 ]:
175.1±27.4 °C

[ 精确质量 ]:
402.225372

[ PSA ]:
105.20000

[ LogP ]:
6.92

[ 外观性状 ]:
透明粘性液体

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.458

[ 储存条件 ]:
室温

[ 水溶解性 ]:
<0.1 g/100 mL

[ 凝固点 ]:
-80℃

乙酰柠檬酸三丁酯MSDS

详细MSDS(安全技术说明书)

乙酰柠檬酸三丁酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TZ8330000

CHEMICAL NAME :: 1,2,3-Propanetricarboxylic acid, 2-(acetyloxy)-, tributyl ester

CAS REGISTRY NUMBER :: 77-90-7

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C20-H34-O8

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 53,774,1964 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 12600 mg/kg/14D-I

TOXIC EFFECTS :: Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 53,774,1964 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3919 No. of Facilities: 88 (estimated) No. of Industries: 4 No. of Occupations: 4 No. of Employees: 1152 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3919 No. of Facilities: 459 (estimated) No. of Industries: 3 No. of Occupations: 17 No. of Employees: 106672 (estimated) No. of Female Employees: 98182 (estimated)

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乙酰柠檬酸三丁酯安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
TZ8330000

[ 海关编码 ]:
2918150000

乙酰柠檬酸三丁酯合成路线

详细合成路线

乙酰柠檬酸三丁酯上下游产品

乙酰柠檬酸三丁酯上游产品

乙酰柠檬酸三丁酯下游产品

乙酰柠檬酸三丁酯制备

由柠檬酸与丁醇酯化；再用醋酐在硫酸催化下进行乙酰化，经减压蒸馏，水洗及中和制得。

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乙酰柠檬酸三丁酯海关

[ 海关编码 ]: 2918150000

[ 中文概述 ]:
2918150000. 柠檬酸盐和柠檬酸酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:4ABxy(出口许可证,入境货物通关单,出境货物通关单出口许可证(加工贸易),出口许可证(边境小额贸易)). 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: 4.出口许可证 A.入境货物通关单 B.出境货物通关单 x.出口许可证(加工贸易) y.出口许可证(边境小额贸易)

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验 N.出口商品检验

[ Summary ]:
2918150000. other salts and esters of citric acid. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:4ABXY(export license,certificate of inspection for goods inward,certificate of inspection for goods outwardexport license(processing trade),export license(border small volume trade)). MFN tariff:6.5%. General tariff:30.0%

乙酰柠檬酸三丁酯文献

Intestinal pregnane X receptor links xenobiotic exposure and hypercholesterolemia.

Mol. Endocrinol. 29 , 765-76, (2015)

Recent studies have associated endocrine-disrupting chemical (EDC) exposure with the increased risk of cardiovascular disease in humans, but the underlying mechanisms responsible for these association...

Mechanistic analysis of PLGA/HPMC-based in-situ forming implants for periodontitis treatment.

Eur. J. Pharm. Biopharm. 94 , 273-83, (2015)

In-situ forming implant formulations based on poly(lactic-co-glycolic acid) (PLGA), acetyltributyl citrate (ATBC), minocycline HCl, N-methyl pyrrolidone (NMP) and optionally hydroxypropyl methylcellul...

Effect of PMMA polymer on the dynamic viscoelasticity and plasticizer leachability of PEMA-based tissue conditioners.

Dent. Mater. J. 29(4) , 374-80, (2010)

The purpose of this study was to determine the effect of PMMA polymer on dynamic viscoelasticity and plasticizer leachability of PEMA-based tissue conditioners. One PEMA polymer and one PMMA polymer w...

更多文献

乙酰柠檬酸三丁酯

乙酰柠檬酸三丁酯用途

乙酰柠檬酸三丁酯名称

乙酰柠檬酸三丁酯生物活性

乙酰柠檬酸三丁酯物理化学性质

乙酰柠檬酸三丁酯MSDS

详细MSDS(安全技术说明书)

乙酰柠檬酸三丁酯毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

乙酰柠檬酸三丁酯安全信息

乙酰柠檬酸三丁酯合成路线

详细合成路线

乙酰柠檬酸三丁酯上下游产品

乙酰柠檬酸三丁酯上游产品

乙酰柠檬酸三丁酯下游产品

乙酰柠檬酸三丁酯制备

乙酰柠檬酸三丁酯海关

乙酰柠檬酸三丁酯文献

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