乙酰柠檬酸三丁酯

Acetyl tributyl citrate (Tributyl O-acetylcitrate; ATBC) 是一种替代增塑剂。

[ 描述 ]:

[ 相关类别 ]:

[参考文献]

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
418.1±40.0 °C at 760 mmHg

[ 熔点 ]:
-59 °C

[ 分子式 ]:
C₂₀H₃₄O₈

[ 分子量 ]:
402.479

[ 闪点 ]:
175.1±27.4 °C

[ 精确质量 ]:
402.225372

[ PSA ]:
105.20000

[ LogP ]:
6.92

[ 外观性状 ]:
透明粘性液体

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.458

[ 储存条件 ]:
室温

[ 水溶解性 ]:
<0.1 g/100 mL

[ 凝固点 ]:
-80℃

详细MSDS(安全技术说明书)

CHEMICAL IDENTIFICATION

RTECS NUMBER :

TZ8330000

CHEMICAL NAME :

1,2,3-Propanetricarboxylic acid, 2-(acetyloxy)-, tributyl ester

CAS REGISTRY NUMBER :

77-90-7

LAST UPDATED :

199701

DATA ITEMS CITED :

5

MOLECULAR FORMULA :

C20-H34-O8

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

>4 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 53,774,1964 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

12600 mg/kg/14D-I

TOXIC EFFECTS :

Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :

JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 53,774,1964 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3919 No. of Facilities: 88 (estimated) No. of Industries: 4 No. of Occupations: 4 No. of Employees: 1152 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3919 No. of Facilities: 459 (estimated) No. of Industries: 3 No. of Occupations: 17 No. of Employees: 106672 (estimated) No. of Female Employees: 98182 (estimated)

[ 个人防护装备 ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
TZ8330000

[ 海关编码 ]:
2918150000

详细合成路线

乙酰柠檬酸三丁酯上游产品

乙酰柠檬酸三丁酯下游产品

由柠檬酸与丁醇酯化；再用醋酐在硫酸催化下进行乙酰化，经减压蒸馏，水洗及中和制得。

[ 海关编码 ]: 2918150000

[ 中文概述 ]:
2918150000. 柠檬酸盐和柠檬酸酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:4ABxy(出口许可证,入境货物通关单,出境货物通关单出口许可证(加工贸易),出口许可证(边境小额贸易)). 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: 4.出口许可证 A.入境货物通关单 B.出境货物通关单 x.出口许可证(加工贸易) y.出口许可证(边境小额贸易)

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验 N.出口商品检验

[ Summary ]:
2918150000. other salts and esters of citric acid. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:4ABXY(export license,certificate of inspection for goods inward,certificate of inspection for goods outwardexport license(processing trade),export license(border small volume trade)). MFN tariff:6.5%. General tariff:30.0%

Intestinal pregnane X receptor links xenobiotic exposure and hypercholesterolemia.

Mol. Endocrinol. 29 , 765-76, (2015)

Recent studies have associated endocrine-disrupting chemical (EDC) exposure with the increased risk of cardiovascular disease in humans, but the underlying mechanisms responsible for these association...

Mechanistic analysis of PLGA/HPMC-based in-situ forming implants for periodontitis treatment.

Eur. J. Pharm. Biopharm. 94 , 273-83, (2015)

In-situ forming implant formulations based on poly(lactic-co-glycolic acid) (PLGA), acetyltributyl citrate (ATBC), minocycline HCl, N-methyl pyrrolidone (NMP) and optionally hydroxypropyl methylcellul...

Effect of PMMA polymer on the dynamic viscoelasticity and plasticizer leachability of PEMA-based tissue conditioners.

Dent. Mater. J. 29(4) , 374-80, (2010)

The purpose of this study was to determine the effect of PMMA polymer on dynamic viscoelasticity and plasticizer leachability of PEMA-based tissue conditioners. One PEMA polymer and one PMMA polymer w...

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公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐经理

产品详情：2-乙酰氧基丙烷-1,2,3-三羧酸三丁酯

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公司名：南通润丰石油化工有限公司

区域：南通市崇川区

价格：
￥需询单/1kg ￥需询单/1ton

联系人：曹经理

产品详情：乙酰柠檬酸三丁酯

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公司名：上海吉至生化科技有限公司

区域：上海市奉贤区

价格：
￥308.0/500ml ￥98.0/100ml

联系人：刘佳

产品详情：乙酰柠檬酸三丁酯

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公司名：上海创赛科技有限公司

区域：上海市嘉定区

价格：
￥221.0/500ml ￥65.0/100ml ￥903.0/2500ml ￥35.0/25ml

联系人：夏言

产品详情：[Perfemiker]乙酰柠檬酸三丁酯,97%

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公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥29.9/25ml ￥61.9/100ml ￥892.9/3l ￥222.9/500ml

联系人：阿拉丁

产品详情：乙酰柠檬酸三丁酯

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