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胶原酶

胶原酶用途

N-3-(2-呋喃基)丙烯酰基-亮氨酸-甘氨酸-脯氨酸-丙氨酸或FALGPA是一种类似于胶原蛋白一级结构的合成物质，可以被所有已知的胶原酶水解。

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胶原酶名称

[ CAS 号 ]:
78832-65-2

[ 中文名 ]:
FA-亮氨酰甘氨酰脯氨酰丙氨酰-OH

[ 英文名 ]:
N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala

[中文别名 ]:

胶原酶

[英文别名 ]:

COLLAGENASE SUBSTRATE II
EINECS 232-582-9
COLLAGENASE GRADE II
FA-LEU-GLY-PRO-ALA-OH
clostridiopeptidase
COLLAGENASE GRADE I

胶原酶生物活性

[ 描述 ]:

FA-Leu-Gly-Pro-Ala-OH 是微生物胶原酶的底物

[ 相关类别 ]:

研究领域 >> 其他

[参考文献]

[1]. Hydrolysis of the Leu-Gly bond of phenylazobenzyl-oxycarbonyl-L-Pro-L-Leu-Gly-L-Pro-D-Arg (a substrate of microbial collagenases) by treponemes isolated from the subgingival plaque of periodontitis patients. Current Microbiology 20, 69-74 (1990).

胶原酶物理化学性质

[ 密度 ]:
1.269g/cm3

[ 沸点 ]:
859.8ºC at 760 mmHg

[ 分子式 ]:
C₂₃H₃₂N₄O₇

[ 分子量 ]:
476.52300

[ 闪点 ]:
473.8ºC

[ 精确质量 ]:
476.22700

[ PSA ]:
158.05000

[ LogP ]:
1.63080

[ 外观性状 ]:
白色或浅褐色粉末

[ 折射率 ]:
1.564

[ 储存条件 ]:
20°C

胶原酶MSDS

详细MSDS(安全技术说明书)

胶原酶安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

胶原酶文献

Aeromonas piscicola AH-3 expresses an extracellular collagenase with cytotoxic properties.

Lett. Appl. Microbiol. 60(3) , 288-97, (2015)

The aim of this study was to investigate the presence and the phenotypic expression of a gene coding for a putative collagenase. This gene (AHA_0517) was identified in Aeromonas hydrophila ATCC 7966 g...

Cell-associated collagenolytic activity by Candida albicans.

Mycopathologia 153(3) , 125-8, (2002)

Cell associated collagenolytic activity of Candida albicans was quantified by measuring the degradation of synthetic peptide 2-furanacryloyl-Leu-Gly-Pro-Ala (FALGPA), which is a specific substrate for...

University of Wisconsin solution inhibits the class II collagenase within crude Clostridium histolyticum collagenase.

Transplant. Proc. 27(6) , 3286, (1995)

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胶原酶