氯华法林

氯华法林用途

Coumachlor is a first genereation anticoagulant rodenticide which blocks formation of prothrombin and inhibits blood coagulation causing death by internal haemorrhage.

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氯华法林名称

[ CAS 号 ]:
81-82-3

[ 中文名 ]:
氯灭鼠灵

[ 英文名 ]:
COUMACHLOR

[中文别名 ]:

[英文别名 ]:

UNII:UCD8XZW42P
MFCD00012094
3-(a-Acetonyl-p-chlorobenzyl)-4-hydroxycoumarin
tomorin
Coumachlor
Geigy Rodenticide Exp.332
FAMARIN
ratilan
P-CHLOROWARFARIN
cumachloor

氯华法林物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
543.1±50.0 °C at 760 mmHg

[ 熔点 ]:
168-170 °C(lit.)

[ 分子式 ]:
C₁₉H₁₅ClO₄

[ 分子量 ]:
342.773

[ 闪点 ]:
282.3±30.1 °C

[ 精确质量 ]:
342.065887

[ PSA ]:
67.51000

[ LogP ]:
4.01

[ 外观性状 ]:
淡黄色粉末

[ 蒸汽压 ]:
0.0±1.5 mmHg at 25°C

[ 折射率 ]:
1.641

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

氯华法林MSDS

氯华法林毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GN4830000

CHEMICAL NAME :: Coumarin, 3-(alpha-acetonyl-p-chlorobenzyl)-4-hydroxy-

CAS REGISTRY NUMBER :: 81-82-3

BEILSTEIN REFERENCE NO. :: 1689759

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C19-H15-Cl-O4

MOLECULAR WEIGHT :: 342.79

WISWESSER LINE NOTATION :: T66 BOVJ DY1V1&R DG& EQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 187 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,186,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 33 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,186,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 392 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 30,531,1995

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 221 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 30,531,1995

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氯华法林安全信息

[ 符号 ]:

GHS08

[ 信号词 ]:
Warning

[ 危害声明 ]:
H373-H412

[ 警示性声明 ]:
P273

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R48/22;R52/53

[ 安全声明 (欧洲) ]:
S37-S61

[ 危险品运输编码 ]:
UN 2811 6.1/PG 1

[ WGK德国 ]:
2

[ RTECS号 ]:
GN4830000

[ 包装等级 ]:
II

[ 危险类别 ]:
6.1(a)

氯华法林合成路线

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